The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

By H. Peinado, S. Lavotshkin, D. Lyden. Seminars in Cancer Biology, 2011

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Extracellular vesicles in cancer: cell-to-cell mediators of metastasis (2016, background): “Cancer cellderived EVs promote angiogenesis and coagulation, modulate the immune system, and remodel surrounding parenchymal tissue, which together support tumor progression (Ciardiello et al., 2016; Peinado et al., 2011; Ratajczak et al., 2006; van der Pol et al., 2012).”
Revisiting the hallmarks of cancer. (2017, positive): “[135] Peinado H, Lavotshkin S and Lyden D.”
Hallmarks of cancer: the next generation. (2011, positive): “As further discussed below, however, certain tissue microenviroments may be preordained to be intrinsically hospitable to disseminated cancer cells (Peinado et al., 2011; Talmadge and Fidler, 2010).”
Classification, Functions, and Clinical Relevance of Extracellular Vesicles (2012, background): “, 2007), but these mechanisms have been summarized excellently elsewhere (Zöller, 2009; Rak, 2010; Peinado et al., 2011).”