Hallmarks of cancer: the next generation.

By D. Hanahan, R. Weinberg. Cell, 2011

63,567 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/6b5cc718b568554ade3850005bb6e76961ff83ed

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Citations in the corpus

Pan-cancer analysis of whole genomes (2020, background): “One of the hallmarks of cancer is the ability of cancer to evade cellular senescence 21 .”
Dragging ras back in the ring. (2014, background): “…have been identified in these assays, including those involved in DNA repair, cellular metabolism, RNA splicing, and the other hallmarks of cancer (Hanahan and Weinberg, 2011), those in the tyrosine kinase-Ras pathway stand out as the major drivers and have been the richest source of targets of…”
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis (2015, background): “to two distinct cell fates (32,33). Second, if one or both TFs auto-activate themselves strongly in addition to strongly repressing the other TF, the circuit can allow for three distinct phenotypes ± (1, 0), (0, 1) and (, ) ± or (high A, low B), (low A, high B) and (medium A, medium B). The (, ) sta”
In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior (2015, background): “Because activating migration and invasion is one of the hallmarks of cancer (Hanahan and Weinberg, 2000, 2011) and key to metastasis (Nguyen et al., 2009), the transfer of biomolecules, including mRNAs involved in migration, may affect not only the migratory behavior but also the metastatic…”
In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform (2016, background): “While it is possible to incorporate smooth muscle cells, pericytes, and lymphatic drainage within these models, the lack of such vessel characteristics is a hallmark of irregularly formed tumor vasculature (Hanahan and Weinberg, 2011; Zheng et al., 2012; Wong et al., 2013).”
Metabolic reprogramming and epigenetic modifications on the path to cancer (2021, background): “Metabolic reprogramming is one of the major features of cancer, during which characteristics of metabolic enzymes, upstream regulating molecules and downstream metabolic products, known as metabolites, are altered (DeBerardinis et al., 2008b; Heiden et al., 2009; Jones and Thompson, 2009; Hanahan an”
RNA-Binding Proteins in Cancer: Old Players and New Actors. (2017, background): “In this context, RBPs are not an exception, and there is already ample experimental evidence that altered RBP function has a significant impact on cancer phenotypes [16] (Table 1).”