The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects.

By Anna Kassinen, Lotta Krogius-Kurikka, H. Mäkivuokko, T. Rinttilä, L. Paulin, Jukka Corander, Erja Malinen, J. Apajalahti, A. Palva. Gastroenterology, 2007

997 citations recorded by the source corpus.

Subfields: Gastroenterology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e0e632db8154636482a10e6b1736a1e507f36455

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Citations in the corpus

Principles and clinical implications of the brain–gut–enteric microbiota axis (2009, background): “A departure from the physiological balance of the enteric microbiota has been suggested as a factor in the pathophysiology of IBS, a condition in which abnormal gastrointestinal motility and secretion is implicated as a cause of alterations in bowel habits”
Intestinal microbiota in human health and disease: the impact of probiotics (2011, methodology): “C based profiling Clone library sequencing (16S) qPCR Kassinen et al. (2007)* Duodenal biopsies Faeces 41 IBS patients 26 Healthy individuals FISH qPCR Kerckhoffs et al. (2009)# Faeces 10 (?”
Short-Term Antibiotic Treatment Has Differing Long-Term Impacts on the Human Throat and Gut Microbiome (2010, background): “Increasing evidence has linked some members of the Actinobacteria to human health [34,35].”
Gut microbiota composition correlates with diet and health in the elderly (2012, methodology): “Raw sequencing reads were quality trimmed using the QIIME pipeline(39) according to the following criteria: (1) exact matches to primer sequences and barcode tags, (2) no ambiguous bases (Ns); (3) read-lengths not shorter than 150 base pairs (bp) or longer than 350 bp; (4) the average quality score ”
Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease (2012, background): “The fecal microbiota of individuals with IBS differs greatly from that of healthy individuals [130].”
The first 1000 cultured species of the human gastrointestinal microbiota (2014, background): “Several studies of the microbiota of irritable bowel syndrome patients and controls have shown that organisms related to these misclassified Ruminococcus spp. are significantly elevated in patients (Kassinen et al., 2007; Rajili c-Stojanovi c et al., 2011; Saulnier et al., 2011).”
Composition, variability, and temporal stability of the intestinal microbiota of the elderly (2010, background): “Changes in the adult gut microbiota have been linked to undesirable health conditions including obesity (10), inflammatory bowel disease (IBD) (11), and irritable bowel syndrome (IBS) (12).”
The role of microbiome in central nervous system disorders (2013, positive): “Moreover, gut microbiome alteration was observed in IBS patients, exemplified by the reduction of species under Lactobacillus genus and Clostridium class (Kassinen et al., 2007; Malinen et al., 2005).”
Diversity of Bifidobacteria within the Infant Gut Microbiota (2012, background): “Furthermore, microbial dysbiosis has been linked to several functional gut disorders, such as inflammatory bowel disease [4,5], irritable bowel syndrome [6], stomach cancer [7], mucosa-associated lymphoid tissue lymphoma [8], obesity [9,10] and necrotizing enterocolitis [11].”