Composition, variability, and temporal stability of the intestinal microbiota of the elderly

By Marcus J. Claesson, S. Cusack, Orla O'Sullivan, Rachel Greene-Diniz, Heleen de Weerd, E. Flannery, Julian R. Marchesi, Daniel Falush, Ted G. Dinan, G. FitzGerald and 13 more. Proceedings of the National Academy of Sciences of the United States of America, 2010

1,700 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1b8ac6743034a1d96737b0a9da80922df52cace6

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Citations in the corpus

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction (2017, positive): “Numerous studies have demonstrated that there are characteristic changes in gut microbial communities in elderly humans (Claesson et al., 2011; M€ akivuokko et al., 2010; Mariat et al., 2009; Zwielehner et al., 2009) and that these changes correlate with health status in the elderly population (Bart”
Human genetics shape the gut microbiome. (2014, neutral): “, 2010), participant age (Claesson et al., 2011), population (Yatsunenko et al.”
Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes (2015, background): “A total of 63% of all the investigated genomes contained the NAD biosynthesis pathways.”
Minireview: Gut microbiota: the neglected endocrine organ. (2014, background): “Homeostatic mechanisms within the microbiota become less effective in the elderly, and it is clear that the microbiota diverges between those who age healthily and those whose health deteriorates with age (30, 31).”
The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota (2017, background): “In contrast, the gut microbiota of adults is specific to an individual and is relatively stable (350).”
The composition of the gut microbiota throughout life, with an emphasis on early life (2015, background): “Vaginally delivered infants, but not infants born by C-section, shared a significantly higher proportion of gut microbiota 16S rRNA gene sequences with their own mother than with other mothers for up to 2 years of age, particularly within the Bacteroidetes and Firmicutes phyla (35).”
Diversity of Bifidobacteria within the Infant Gut Microbiota (2012, background): “The adult human gut microbiota is considered to be more complex than its infant equivalent, while being stable over time and similar between individuals [12,15].”
Moving pictures of the human microbiome (2011, background): “…our observations paint a picture of a human microbiome that is highly variable over time (Figures 2 and 3; Additional files 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15), but from which stable patterns of similarities and differences among body habitats and individuals emerge (Figure 1).”