Helicobacter pylori and gastrointestinal tract adenocarcinomas

By R. Peek, Martin J. Blaser. Nature Reviews. Cancer, 2002

1,857 citations recorded by the source corpus.

Subfields: Epidemiology, Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/e042e5067c762f2cf653db6ce12a7f00d8ebb9de

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Martin J. Blaser
2. R. Peek
3. M. Karin
4. B. Goodman
5. F. Greten
6. H. Gardner

In Pulmonary and Respiratory Medicine

1. Martin J. Blaser
2. R. Peek

In Surgery

1. R. Peek
2. Martin J. Blaser
3. B. Goodman
4. H. Gardner
5. Keith T. Wilson
6. Lydia E. Wroblewski
7. Masanori Hatakeyama

Citations in the corpus

• Microbiome and Malignancy (2011, background): “The traditional model of gastric carcinogenesis focuses on host, strain, or interaction differences in explaining H. pyloriinduced gastric adenocarcinoma (Peek and Blaser, 2002).”
• Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk (2010, background): “pylori organisms are able to send and receive signals from their hosts, allowing host and bacteria to become linked in a dynamic equilibrium (161, 242).”
• The microbiome and cancer (2018, background): “Fusobacterium Increase in IL-6, IL-8, IL-18 and NF-κB signalling Kostic et al (2013) [46] Rubinstein et al (2013) [52] Helicobacter Increase in IL-1B, IL-8 and NF-κB signalling through CagA Peek and Blaser (2002) [58]”
• Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse (2008, background): “Infection with Helicobacter pylori is the strongest risk factor for the development of gastric adenocarcinoma (2).”
• Helicobacter pylori: gastric cancer and beyond (2010, background): “pylori strain that expressed lex and ley, only bacterial populations recovered from leb-positive mice expressed leb, and this was mediated by a putative galactosyltransferase gene (β‐(1,3)galT)38.”
• NF-κB in cancer: from innocent bystander to major culprit (2002, background): “aspx?version=provider&viewid=74bd04b7-e9b2-47db-b634-93f8fbd71ee2">gastric cancer — the second most common malignancy worldwide — is Helicobacter pylori infectio”
• Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. (2003, neutral): “IL-1B-511 C/C 21 (40) 50 (46) 57 (45) 47 (25) 104 (50) C/T 21 (40) 46 (43) 56 (44) 98 (52) 97 (46) T/T 11 (20) 12 (11) 13 (11) 43 (23) 9 (4) IL-1RN 1/1 30 (57) 49 (46) 69 (55) 81 (43) 114 (55) 1/2 12 (23) 40 (37) 42 (33) 59 (31) 76 (36) 1/3,4 2 (3) 10 (9) 3 (2) 2 (1) 7 (3) 2/2 8 (15) 8 (7) 12 (10) 4”