Ubiquitin and proteasomes: Themes and variations on ubiquitylation

By A. Weissman. Nature reviews. Molecular cell biology, 2001

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Bcl10 activates the NF-κB pathway through ubiquitination of NEMO (2004, background): “K48-linked polyubiquitination generally targets proteins for degradation in the proteasome, whereas K63-linked ubiquitination can regulate protein function or protein–protein interaction”
IAP proteins: blocking the road to death's door (2002, background): “This process involves the sequential covalent addition of UBIQUITIN — a 76-residue protein — onto specific lysine residues on the target protei”
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (2002, background): “Ubiquitination and targeted protein degradation within the proteosome complex controls many processes in eukaryotic cells, including meiosis, cellular proliferation and developmen”