Mobilization of vacuolar iron by AtNRAMP3 and AtNRAMP4 is essential for seed germination on low iron

By Viviane Lanquar, F. Lelièvre, S. Bolte, C. Hamès, C. Alcon, D. Neumann, G. Vansuyt, C. Curie, A. Schröder, Ute Krämer and 2 more. EMBO Journal, 2005

606 citations recorded by the source corpus.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/de99e87542dfa68863dd99cc0093f5af1dcec7c6

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In Plant Science

1. J. Ma
2. Martin R. Broadley
3. S. Carvalho
4. Marta W. Vasconcelos
5. P. White
6. Naoki Yamaji
7. Y. Zuo
8. Fusuo Zhang

Citations in the corpus

• Iron and zinc biofortification strategies in dicot plants by intercropping with gramineous species. A review (2011, background): “Other Fe transporter genes, such as AtNRAMP3, AtNRAMP4 and AtVIT1, are all expressed in the vascular system of the roots and shoots, and the proteins that these genes encode appear to play a role in vacuolar Fe homeostasis (Thomine et al., 2003; Lanquar et al., 2005).”
• Ecophysiology of iron homeostasis in plants (2016, background): “2006), and exported to the cytoplasm by natural resistance-associated macrophage proteins NRAMP3 and NRAMP4 (Lanquar et al. 2005).”
• Biofortification of crops with seven mineral elements often lacking in human diets--iron, zinc, copper, calcium, magnesium, selenium and iodine. (2009, background): “…NRAMP3 and NRAMP4 are thought to facilitate Fe2+ release from the vacuole (Thomine et al., 2003; Gross et al., 2003; Hall & Williams, 2003; Lanquar et al., 2005; Grotz & Guerinot, 2006; Puig et al., 2007a), opposing the activity of the vacuolar iron transporter 1 (VIT1) protein which…”
• Iron transport, deposition and bioavailability in the wheat and barley grain (2009, background): “Vacuolar efflux transporters such as Nramp3 and 4 have been shown to be essential for the mobilization of iron from the protein storage vacuoles of the Arabidopsis embryo (Lanquar et al. 2005).”
• The molecular mechanism of zinc and cadmium stress response in plants (2012, neutral): “Mn supply [151, 152].”
• Iron dynamics in the rhizosphere as a case study for analyzing interactions between soils, plants and microbes (2009, background): “Arabidopsis has emerged as an interesting model in this respect because VIT1 was isolated as a transporter for delivery of iron into storage vacuoles of vascular cells in the embryo whereas NRAMP3/ NRAMP4 divalent metal transporters remobilize this vacuolar iron upon germination (Lanquar et al. 2005”
• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “AtNRAMP3 and AtNRAMP4 are responsible for mobilization of vacuolar Fe stores (Thomine et al. , 2003; Lanquar et al. , 2005 ).”
• Nramp5 Is a Major Transporter Responsible for Manganese and Cadmium Uptake in Rice[C][W] (2012, background): “In Arabidopsis, Nramp1, 3, and 4 showed transport activity in yeast for Fe, Mn, and Cd (Curie et al., 2000; Thomine et al., 2000, 2003; Lanquar et al., 2005), whereas Nramp6 only transported Cd but not Fe (Cailliatte et al., 2009).”
• Iron uptake mechanisms in plants: Functions of the FRO family of ferric reductases (2009, background): “Transporters that import and export iron across the vacuolar membrane have been characterized; VIT1 (vacuolar iron transporter 1) imports iron into the vacuole [57], while NRAMP3 and NRAMP4 both export iron from vacuoles [58] (Fig.”
• Plant Responses to Heavy Metal Toxicity (2012, neutral): “(Thomine et al. 2003; Lanquar et al. 2005).”
• Vacuolar transporters and their essential role in plant metabolism. (2006, background): “The final proof of AtNRAMP3 function was presented recently by producing a double knock-out Arabidopsis plant atnramp3/atnramp4 (Lanquar et al., 2005).”
• Heavy Metal Tolerance in Plants: Role of Transcriptomics, Proteomics, Metabolomics, and Ionomics (2016, background): “Furthermore, AtNRAMP3 and AtNRAMP4 have been shown to mediate the remobilization of Fe from the vacuolar store and are essential for seed germination under low Fe conditions (Thomine et al., 2003; Lanquar et al., 2005), indicating a role of Nramps in Fe homeostasis.”