Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling.

By H. Forman, M. Torres. American Journal of Respiratory and Critical Care Medicine, 2002

922 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/dd02f278483674a7ee3d69695f6765dfa5a377df

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. G. Raposo
2. M. Block
3. Jau-Shyong Hong
4. P. Barnes
5. I. Peluso
6. C. Théry

In Molecular Biology

1. G. Raposo
2. S. Amigorena
3. Jau-Shyong Hong
4. P. Barnes
5. Miguel C. Seabra
6. I. Peluso
7. M. Block
8. M. Iriti

In Physiology

1. M. Block
2. Jau-Shyong Hong
3. P. Barnes
4. I. Peluso
5. G. Raposo
6. M. Iriti

Citations in the corpus

• Glucose-6-Phosphate Dehydrogenase, NADPH, and Cell Survival (2012, background): “and macrophages by bacteria or by chemical stimuli such as fmet-leu-phe (40) that is known as the ‘‘respiratory burst.”
• Selenium in Human Health and Disease (2011, neutral): “White blood cells such as lymphocytes, macrophages, and neutrophils require ROS and pro-inflammatory molecules for their activation, differentiation, and phagocytosis (132).”
• Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases (2020, background): “Cellular oxidative metabolism produces free radicals and organic peroxides as by-products during cellular mitochondrial electron transport or through metal-catalyzed oxidation of metabolites and oxidoreductases (Forman and Torres, 2002; Hussain et al., 2016).”
• Mediators of Chronic Obstructive Pulmonary Disease (2004, background): “Indeed, many aspects of macrophage function are regulated by oxidants through the activation of multiple kinase pathways (Forman and Torres, 2002).”
• The Role of Selenium in Inflammation and Immunity: From Molecular Mechanisms to Therapeutic Opportunities (2012, background): “Activation of phagocytic leukocytes such as macrophages and neutrophils through a variety of receptors induces a relatively rapid increase in ROS, that is, phagocytic oxidative burst (75).”
• NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. (2006, background): “Like DCs, macrophages have been shown previously to produce ROS during phagocytosis or after activation (Forman and Torres, 2002).”
• Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. (2005, methodology): “Using PHOX / neuron-glia cultures, we have shown that activation of the PHOX initiates an intracellular ROS signaling pathway (Forman and Torres, 2002) that can activate microglia and amplify the production of pro-inflammatory cytokines, such as TNFa (Qin et al.”