The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation.

By G. Nicolas, C. Chauvet, L. Viatte, J. Danan, X. Bigard, I. Devaux, C. Beaumont, A. Kahn, S. Vaulont. Journal of Clinical Investigation, 2002

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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. (2004, positive): “Importantly, the turpentine-induced hypoferremia was not observed in hepcidin-deficient mice (8), demonstrating that hepcidin is required for iron sequestration during inflammatory conditions.”
Anti‐microbial peptides: from invertebrates to vertebrates (2004, background): “The gene encoding this iron-regulatory peptide is regulated by anemia, hypoxia, and inflammation (91).”
Identification of an intestinal heme transporter. (2005, background): “Exposure of mice to hypoxia for 3 days is known to induce iron absorption (Raja et al., 1988) and reduce levels of the iron-regulatory peptide hepcidin in the liver (Nicolas et al., 2002).”
Anemia of Inflammation (2014, positive): “The response depends on inflammation-induced increase in plasma concentrations of hepcidin.(31) Increased hepcidin degrades cellular ferroportin and traps iron in macrophages, hepatocytes, and intestinal enterocytes so that less iron is delivered to plasma transferrin.”
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). (2007, background): “Discussion Hepcidin is suppressed by both anemia and hypoxia (7).”