Nanoparticulate systems for brain delivery of drugs.

By J. Kreuter. Advanced Drug Delivery Reviews, 2001

1,208 citations recorded by the source corpus.

Subfields: Biomaterials, Neurology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/da563678bfe5445bb9131f56e26d217f4120b247

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. K. El-Say
2. Hossam S. El-Sawy
3. Elif S. Seven
4. Zhili Peng
5. R. Leblanc
6. Yiqun Zhou
7. Omid Veiseh
8. J. Gunn

In Neurology

1. Berislav Zlokovic
2. A. Sagare
3. D. Holtzman
4. R. Deane
5. K. El-Say
6. Hossam S. El-Sawy
7. M. Üner
8. P. Couvreur

In Pharmaceutical Science

1. Elif S. Seven
2. Zhili Peng
3. R. Leblanc
4. Yiqun Zhou
5. A. Rodríguez-Gascón
6. K. El-Say
7. Hossam S. El-Sawy
8. M. Üner

Citations in the corpus

• Nanocarriers’ entry into the cell: relevance to drug delivery (2009, result): “Similar conclusions were drawn from parallel studies performed on PACA nanoparticles PEGylated by the single adsorption of polysorbate 80 [122].”
• Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions (2009, background): “Nanoparticles are made of natural or artificial polymers ranging in size from 10–1000 nm (Kreuter, 2001).”
• Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles (2005, background): “The characteristic biokinetic behaviors of NPs are attractive qualities for promising applications in medicine as diagnostic and therapeutic devices and as tools to investigate and understand molecular processes and structures in living cells (Akerman et al. 2002; Foley et al. 2002; Kreuter 2001; Li”
• Polymeric nanoparticles: Promising platform for drug delivery. (2017, background): “Many explanations can illustrate the mechanism of PNPs uptake and their ability to transfer drugs into the brain (Kreuter, 2014, 2012).”
• Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives (2007, background): “Hydrophilic coating of colloids improves the transport of these through BBB and tissue distribution (Kreuter 2001; Wang et al 2002).”
• Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines (2011, positive): “[66] demonstrates the delivery of several drugs successfully through the blood brain barrier using polysorbate 80 coated PACA nanoparticles [66].”
• apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. (2008, background): “For example, LRP2 mediates transport of apoJ and apoJ-Aβ complexes across the BBB (19, 41), LDLR may transport LDL (42) and LDL apoproteins conjugated to nanoparticles encapsulating pharmaceuticals (43) across the BBB, and LRP1 mediates clearance of unbound Aβ across the BBB (16, 17).”