Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny.
By Takako Isshiki, Bret J. Pearson, Scott Holbrook, C. Doe. Cell, 2001
653 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/d9fa8914f9b9fcea50267fe0588146c8e801950a
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cellular and Molecular Neuroscience
- A. Kriegstein
- V. Martínez‐Cerdeño
- S. Noctor
- Sally Temple
- P. Arlotta
- J. D. Macklis
- W. Huttner
- Jan H. Lui
In Molecular Biology
- A. Kriegstein
- S. Noctor
- Sally Temple
- V. Martínez‐Cerdeño
- Stefan Schumacher
- Haiyan Huang
- L. Smirnova
- Anja Gräfe
In Plant Science
Citations in the corpus
- A Developmental Switch in the Response of DRG Neurons to ETS Transcription Factor Signaling (2005, neutral): “differentiation of early-born neuroblasts [38].”
- Neuronal subtype specification in the cerebral cortex (2007, background): “In this system, progenitors express a sequential series of transcription factors during neurogenesis, followed by the maintained expression of these same transcription factors in the postmitotic progeny that were born during the window of expression of each gene in the progenitor”
- Genomic Analysis of Mouse Retinal Development (2004, background): “The model of temporal changes in competence is strongly supported by recent elegant studies of Drosophila CNS development (Isshiki et al. 2001; Pearson and Doe 2003), where a temporal order of transcription factor expression was found to set the context of cell fate determination.”
- Regulation of miRNA expression during neural cell specification (2005, background): “, 2003), a gene involved in cell fate restriction of neuroblasts (Isshiki et al., 2001).”
- The development of neural stem cells (2001, background): “Drosophila CNS neuroblasts express sequentially the transcription factors Hunchback, Kruppel, POU-domain genes 1 and 2, Castor and grainyhead, which specify the production of different neurons at different time”
- Systematic analysis of neural projections reveals clonal composition of the Drosophila brain. (2013, neutral): “Neuroblasts change their gene expression patterns drastically during neurogenesis [45], some of which control the generation of specific cell types [46].”
- Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion (2006, background): “For example, the genes hunchback ( hb ), Kruppel ( Kr ), pdm1/pdm2 ( pdm ) and castor ( cas ) are expressed in dividing neuroblasts in this order, in early-, mid- and late-born neurons respectivel”