Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice.

By K. Hata, Masaki Okano, Hong Lei, E. Li. Development, 2002

1,046 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/d90873f69acb2f3adb86df995ca250a7a552b9ad

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Citations in the corpus

CpG islands – ‘A rough guide’ (2009, background): “This protein associates with, and facilitates the action of the de novo methyltransferases [50–53].”
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos (2014, background): “Despite divergent development and remethylation dynamics, DNMT3L and DNMT3A are required to establish the sex-specific imprints (Bourc’his et al. 2001; Hata et al. 2002; Bourc’his and Bestor 2004; Kaneda et al. 2004; Kato et al. 2007).”
Establishment and Maintenance of Genomic Methylation Patterns in Mouse Embryonic Stem Cells by Dnmt3a and Dnmt3b (2003, background): “Genetic studies have shown that Dnmt3a and Dnmt3b are involved in the establishment of methylation imprints during gametogenesis (18).”
DNA Methylation and Its Basic Function (2013, background): “A final member of the Dnmt family is Dnmt3L, a protein that lacks the catalytic domain present in other Dnmt enzymes (Aapola et al, 2000; Hata et al, 2002).”
DNA hypomethylation and human diseases. (2007, background): “DNMT3L serves to modulate the activity of DNMT3A and DNMT3B [124,125] and positively regulates the established DNA methylation at imprinted and repeat sequence sites [126–128].”
How is pluripotency determined and maintained? (2007, background): “5 NT Normal Normal Defective Restored Okano et al., 1999; Chen et al., 2003 Dnmt1/3a/3b NT NT Normal Normal Defective Restored Tsumura et al., 2006 Dnmt3l Viable Normal Normal Normal Normal NT Hata et al., 2002 Cgbp (Cxxc1) Die at E6.”