Drosophila immunity: paths and patterns.

By D. Hultmark. Current Opinion in Immunology, 2003

609 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Immunology, Insect Science

View Paper: https://www.semanticscholar.org/paper/d5f0dd36b9c5dcf5f4ec49c28c10184a364bb766

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. B. Lemaître
2. J. Hoffmann
3. B. Lee
4. S. Iwanaga

In Immunology

1. J. Hoffmann
2. B. Lemaître
3. Y. Moret
4. B. Lee
5. S. Iwanaga
6. J. Rolff
7. M. Siva‐Jothy
8. J. Imler

In Insect Science

1. J. Hoffmann
2. B. Lemaître
3. B. Lee
4. S. Iwanaga
5. J. Rolff
6. Y. Moret
7. M. Siva‐Jothy
8. J. Imler

Citations in the corpus

• Immune pathways and defence mechanisms in honey bees Apis mellifera (2006, background): “While Toll signalling in flies serves a dual purpose in development and immunity, the signalling process activated by peptidoglycan recognition protein (PGRP)-LC and Imd is specific for antimicrobial defence and is dispensable for normal development (Hultmark, 2003).”
• Recent advances in the innate immunity of invertebrate animals. (2005, background): “Figure 7 shows two main signaling pathways that regulate the expressions of the antimicrobial genes of Drosophila, which have been extensively reviewed recently (Gobert et al., 2003; Brennan et al., 2004; Hultmark, 2003).”
• The Drosophila immune system detects bacteria through specific peptidoglycan recognition (2003, background): “Drosophila lacks an adaptive immune system and relies solely on innate immune reactions for its defens”
• Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections (2007, background): “The humoral immune response is initiated by the recognition of conserved microbe-specific molecules such as peptidoglycan, leading to the activation of signaling cascades and the nuclear translocation of the NF-κB transcription factors Relish, dorsal and DIF, which induce the transcription of antimi”
• The host defense of Drosophila melanogaster. (2007, background): “A null mutation in ref(2)P is permissive to the Sigma virus, but causes male sterility, indicating that this gene has an endogenous function in flies.”
• The Drosophila Toll Signaling Pathway (2011, background): “The Toll pathway also plays a role in the cellular immune response, which includes the phagocytosis of microbes, and the encapsulation and killing of parasites (15).”
• Insect Immunity: An Evolutionary Ecology Perspective (2005, background): “At the core of the insect immune response (Hultmark, 2003) are two cellbased signal transduction pathways referred to by the name of the transmembrane proteins that mediate them: Toll and Imd (Fig.”