Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes

By S. Stoll, J. Delon, T. Brotz, Ronald N. Germain. Science, 2002

778 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/d4c7943e0f186e837bb7c8a4d649ca43a582d22f

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In Immunology

Citations in the corpus

Antigen-Specific Inhibition of CD8+ T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species1 (2004, background): “Previous studies in vitro and in vivo have indicated that the Ag-specific interaction between T cells and APCs is much more stable and lasts much longer than interaction in the absence of the Ag (42, 43).”
Quantitative challenges in understanding ligand discrimination by αβ T cells (2008, background): “data [26-28], T cells spend 1-5 min with dendritic cells if they fail to find pMHC ligands engendering a ‘stop’ signal [29], and their activation (at least in terms of integrin upregulation that stops motion and promotes effective synapse formation) must be at least that fast.”
The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection (2009, background): “, 2008) and in lymph nodes (Stoll et al., 2002).”
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209+ dendritic cells for immune T cell areas (2010, background): “However, 12 hr after LPS i.v., DC-SIGN+ cells were abundant and localized to T cell areas, regions in which DCs have been shown to present antigens to recirculating antigenspecific T cells (Stoll et al., 2002; Mempel et al., 2004; Miller et al., 2004; Shakhar et al., 2005) (Figure 2C).”
Homing and cellular traffic in lymph nodes (2003, methodology): “In experiments by Stoll et al.(123), fluorescent-labelled TCR-transgenic lymphocytes were injected intravenously and antigen-pulsed DCs labelled with a different fluorophore were injected into the skin.”