Requirement of Heterochromatin for Cohesion at Centromeres

By P. Bernard, Jean-François Maure, J. Partridge, Sylvie Genier, J. Javerzat, Robin C. Allshire. Science, 2001

647 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/d3d20c76c286043ce4a43c00b2e9af92fde0f3fc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. C. Haering
2. Kim Nasmyth

In Molecular Biology

1. C. Haering
2. Kim Nasmyth
3. Ian R. Henderson
4. R. Martienssen
5. Z. Lippman
6. S. White
7. Steven E. Jacobsen
8. Aline V. Probst

In Plant Science

1. Ian R. Henderson
2. Steven E. Jacobsen
3. R. Martienssen
4. C. Haering
5. Z. Lippman
6. Kim Nasmyth
7. S. White
8. Robin C. Allshire

Citations in the corpus

• RNAi-mediated chromatin silencing in fission yeast. (2008, background): “Consistent with this, cells with a mild lesion in the Rad21 cohesin subunit require Swi6/heterochromatin for viability (Bernard et al. 2001).”
• Epigenetic inheritance in plants (2007, background): “However, heterochromatin can also have important roles during chromosomal segregatio”
• Epigenetic inheritance during the cell cycle (2009, background): “Swi6 recruits the evolutionarily conserved ring-shaped protein complex cohesin, which maintains sister chromatid cohesio”
• The role of RNA interference in heterochromatic silencing (2004, background): “, which in turn recruits cohesin — a highly conserved protein required for sister-chromatid cohesion and chromosome segregation during mitosi”
• Cohesins functionally associate with CTCF on mammalian chromosome arms. (2008, positive): “…centromeric cohesins are recruited via different mechanisms: in S. pombe, cohesins are recruited to constitutive heterochromatin via Swi6, a homolog of HP1, which binds to histone H3 methylated at lysine 9 (H3K9me) as well as to cohesin subunits (Bernard et al., 2001; Nonaka et al., 2002).”
• The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis (2004, background): “As heterochromatin is required to recruit large amounts of cohesin to centromere”
• Genome-Wide Mapping of the Cohesin Complex in the Yeast Saccharomyces cerevisiae (2004, neutral): “The preferential location of cohesin in heterochromatin in S. pombe also supports the idea of chromatin modification/ structure as the basis for cohesin localization (Bernard et al. 2001; Nonaka et al. 2002).”
• Cohesin: its roles and mechanisms. (2009, background): “amounts of pericentric cohesin and defective centromeric sister chromatid cohesion (8, 125).”