Actin-based plasticity in dendritic spines.

By A. Matus. Science, 2000

846 citations recorded by the source corpus.

Subfields: Biophysics, Cell Biology, Cellular and Molecular Neuroscience

View Paper: https://www.semanticscholar.org/paper/d34dc7846d0ebee7d5981167f3167b211b706e93

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Citations in the corpus

Pyramidal neurons: dendritic structure and synaptic integration (2008, background): “By contrast, low-level activation of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors (AMPARs) stabilizes spines, suggesting a dual role for glutamate-receptor activation in promoting structural plasticit”
Balancing structure and function at hippocampal dendritic spines. (2008, background): “…of filopodia and mediates the expansion of spine heads with LTP and the shrinkage of spine heads with LTD. Chen et al. 2004, Fukazawa et al. 2003, Matus 2000, Kim & Lisman 1999, Krucker et al. 2000, Lin et al. 2005, Nagerl et al. 2004, Ouyang et al. 2005, Star et al. 2002, Zhou et al. 2004…”
Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear (2010, positive): “In keeping with this, LTP induces a lasting increase in polymerized actin in dendritic spines (132), and a reduction in actin-based spine motility underlies spine stabilization (282).”
Dentritic spines : structure, dynamics and regulation (2001, background): “Advances in video microscopy and GFP technology have revealed that most spines can change shape over a timescale of seconds to minutes in cultured neurons, brain slices and the intact brai”
Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. (2004, positive): “Postsynaptic actin-rich dendritic spines are dynamically involved in synaptic plasticity, learning, and memory (Fukazawa et al., 2003; Matus, 2000; Star et al., 2002).”
Structure and function of dendritic spines. (2002, background): “With synapse formation and maturation, consisting, in part, of AMPA receptor insertion (104) and perhaps recruitment of adhesion molecules to synaptic junctions (105), the synapse is stabilized, and motility decreases (90).”
Experience-dependent structural synaptic plasticity in the mammalian brain (2009, background): “, and the supposition that spine twitching modulates synaptic functio”
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. (2009, background): “It is generally believed that changes in spine morphology are based on rearrangements of the actin cytoskeleton (Ethell and Pasquale, 2005; Matus, 2000; Tada and Sheng, 2006).”
Regulatory mechanisms of AMPA receptors in synaptic plasticity (2007, background): “The shape, size and number of spines are profoundly influenced by signal transduction pathways that affect the equilibrium between filamentous and globular acti”
Structural plasticity and memory (2004, background): “Actin, for example, can be rapidly polymerized and induce cytoskeletal rearrangements that culminate in new synaptic structure”
Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy (2008, background): “Notably, actin is highly enriched at dendritic spines, specialized postsynaptic compartments that mediate most of the excitatory synaptic transmission in the brai”