Amphipathic α helical antimicrobial peptides.

By A. Giangaspero, L. Sandri, A. Tossi. 2001

622 citations recorded by the source corpus.

Subfields: Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/d095db0de148c86c8ab2c4365fe6108359d38ab3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Microbiology

1. K. Brogden
2. M. Malmsten
3. A. Schmidtchen
4. Mukesh Pasupuleti
5. Robert E. W. Hancock
6. M. Zanetti

In Molecular Biology

1. K. Brogden
2. Lin F. Yang
3. M. Malmsten
4. Mukesh Pasupuleti
5. S. Merkle
6. Campbell J. Nairn
7. A. Schmidtchen

Citations in the corpus

• Restoration of threatened species: a noble cause for transgenic trees (2007, background): “Synthetic derivatives of these “natural” peptides have been shown to be efficient antimicrobial agents against many plant and animal pathogens (Schwab et al. 1999; Osusky et al. 2000; Tossi et al. 2000; Gura 2001; Rajasekaran et al. 2001; Ballweber et al. 2002).”
• Dermcidin: a novel human antibiotic peptide secreted by sweat glands (2001, background): “As modeling studies suggest, like many antimicrobial peptides—including insect cecropins, frog magainins and some mammalian cathelicidins—DCD is likely to adopt an amphipathic α-heli”
• Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus (2005, methodology): “The effect of treatment was evaluated in two different ways: (1) a reduction in peritoneal bacterial counts in actively treated as compared with untreated control mice, or (2) survival for up to seven days after active treatment as compared with untreated controls.”
• Barrel-stave model or toroidal model? A case study on melittin pores. (2001, background): “Interestingly, melittin has similar molecular characteristics as antimicrobial peptides, and its action on cell membranes is also similar (Tossi et al., 2000).”
• Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? (2005, background): “A second subgroup contains ∼290 cationic peptides, which are short (contain”
• Antimicrobial peptides: key components of the innate immune system (2012, background): “…that hydrophobicity can modulate the antimicrobial efficiency and specificity of individual α-helical AMPs, as hydrophobicity governs the extent to which a peptide can partition into the lipid bilayers (Giangaspero et al., 2001; Dennison et al., 2005a; Ringstad et al., 2007; Ringstad et al., 2008).”