Innate and Adaptive Immunity in the Pathogenesis of Atherosclerosis

By G. Hansson, Peter Libby, U. Schönbeck, Zhong‐qun Yan. Circulation Research, 2002

1,085 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ceb0738ee45dfe46c8b1d73c0af854803db6df49

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Peter Libby
2. P. Ridker
3. G. Hansson
4. Z. Mallat
5. A. Tedgui
6. I. Tabas
7. Jongsoon Lee
8. L. Melvin

In Immunology

1. Peter Libby
2. G. Hansson
3. P. Ridker
4. Z. Mallat
5. A. Tedgui
6. I. Tabas
7. P. Calder
8. Jongsoon Lee

In Molecular Biology

1. Peter Libby
2. P. Ridker
3. G. Hansson
4. Richard C. Becker
5. A. Tedgui
6. Z. Mallat

Citations in the corpus

• Atherosclerosis: Process, Indicators, Risk Factors and New Hopes (2014, background): “Immune and infection mediated atherosclerosis Mediators of acquired and innate immunity are involved in atherosclerosis, as might be anticipated for a chronic inflammatory process.([80]) In the chronic state, atheromata contain activated macrophages, T lymphocytes and mast cells, which are also pres”
• Innate and acquired immunity in atherogenesis (2002, background): “Among these, it is now apparent that the immune system, when considered in the broadest context, is one of the dominant factors, aside from cholesterol, modulating atherogenesi”
• Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL (2003, background): “Moreover, growing evidence suggests that both adaptive and innate immune mechanisms can modulate the progression of atherosclerosi”
• Cytokines in atherosclerosis: pathogenic and regulatory pathways. (2006, background): “Both humoral and cellular immune responses can profoundly affect atherosclerotic development and progression (268).”
• Inflammation in Atherosclerosis: From Pathophysiology to Practice (2009, background): “(4) Primitive phagocytic cells, evolutionary precursors of the mammalian monocyte/macrophage (Figure 1), exist in marine invertebrates as recognized by Metchnikoff in the 19th century.”
• COVID-19 update: Covid-19-associated coagulopathy (2020, background): “The available evidence suggests that ~ 90% of intact megakaryocytes of pulmonary origin remain in the microcirculation of the lungs; however, an increased proportion can leave and enter the arterial circulation in the presence of lung infection and inflammation [79].”
• Mast Cell: A Multi-Functional Master Cell (2016, background): “Mast cell proteases degrade collagen in the fibrous cap of the plaque, which can lead to plaque rupture (58).”