Identification of the tumour transition states occurring during EMT

By I. Pastushenko, A. Brisebarre, A. Sifrim, M. Fioramonti, Tatiana Revenco, Soufiane Boumahdi, Alexandra Van Keymeulen, D. Brown, V. Moers, Sophie Lemaire and 15 more. Nature, 2018

1,340 citations recorded by the source corpus.

Subfields: Cancer Research, Cell Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/ceaa39aa4b9066ae5e94ffc791cd4d1ae07890b6

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Citations in the corpus

Inflammation and Cancer: Triggers, Mechanisms and Consequences (2019, background): “However, the best known case of cancer cell plasticity is through their ability to undergo various states of EMT and MET (Gupta et al., 2019; Pastushenko et al., 2018; Varga and Greten, 2017) and re-establishment of cancer stem cell pool during metastasis or therapy (de Sousa e Melo et al.”
The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis (2022, background): “Related studies have shown that different EMTs have different characteristics of infiltration, metastasis, and differentiation, when the cells of mixed epithelium and mesenchyme play a greater role in reaching circulation, colonization, and metastasis [14].”
Epithelial-mesenchymal plasticity in cancer progression and metastasis (2019, background): “As discussed earlier, tumor cells often undergo an incomplete EMT during metastasis and recent studies have confirmed the existence of these partial EMT states during tumor progression in vivo (Pastushenko et al., 2018; Yu et al., 2013).”
Dynamic EMT: a multi‐tool for tumor progression (2021, positive): “Another group identified different tumor transition states occurring during EMT in cancer progression and introduced the term “hybrid” EMT (Pastushenko et al , 2018; Pastushenko & Blanpain, 2019; Pastushenko et al , 2021) (Fig 1B).”
TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis (2019, background): “These EMT subpopulations displayed differences in cellular plasticity, invasiveness, and metastatic potential, and tumor cells with an early stage of EMT were most likely to metastasize [67].”
Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies (2023, background): “279 Autophagy supplies the energy required for TGF-β – induced EMT and cancer metastasis.”