Disruption of dendritic translation of CaMKIIα impairs stabilization of synaptic plasticity and memory consolidation

By S. Miller, Masahiro Yasuda, Jennifer K. Coats, Ying Jones, M. E. Martone, M. Mayford. 2002

140 citations recorded by the source corpus.

Citations in the corpus

mRNA Localization: Gene Expression in the Spatial Dimension (2009, unknown): “…et al. (2000) defined a 94 nucleotide-long element in the 30UTR of CamKIIa that was sufficient for dendritic localization of the transcript, whereas Miller et al. (2002) showed that CamKIIa mRNA containing the 94 nucleotide element but lacking the rest of the 30UTR was not dendritically localized…”
Dendritic protein synthesis, synaptic plasticity, and memory. (2006, unknown): “These results raise the possibility that local synthesis of CAMKIIα is necessary for late LTP as well as the establishment of long-term hippocampal-dependent memories.”
Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity (2008, unknown): “Unlike the L-LTP and long-term memory, the E-LTP and short-term memory were unaffected by this mutation (Miller et al., 2002).”
BDNF-induced local protein synthesis and synaptic plasticity. (2014, unknown): “However, additional studies showed that CaMKIIa mRNA containing this element but lacking most of the 30UTR fail to be targeted to dendrites in vivo (Miller et al., 2002).”
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. (2004, unknown): “ablation of the subset of αCaMKII mRNA localized to dendrites caused deficits in LTP and spatial and contextual memory (Miller et al., 2002).”