ExoCarta: A compendium of exosomal proteins and RNA

By Suresh Mathivanan, Richard J. Simpson. Proteomics, 2009

869 citations recorded by the source corpus.

Subfields: Cancer Research, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/cccc79157702b4c4030566c970124dd10f6b1669

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. C. Théry
2. Suresh Mathivanan
3. Hina Kalra
4. Richard J. Simpson
5. E. Batrakova
6. G. Raposo
7. M. Kim
8. Marina Colombo

In Materials Chemistry

1. C. Théry
2. Hina Kalra
3. Suresh Mathivanan
4. H. Ji
5. Richard J. Simpson
6. Jianguo Xia
7. Ramesh C. Gupta
8. Le Chang

In Molecular Biology

1. C. Théry
2. Suresh Mathivanan
3. Richard J. Simpson
4. Hina Kalra
5. G. Raposo
6. Marina Colombo
7. E. Batrakova
8. H. Ji

Citations in the corpus

• Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake (2016, neutral): “Three different databases are publicly accessible: Exocarta, Vesiclepedia, and EVpedia (Kim et al. 2013; Kalra et al. 2012; Mathivanan and Simpson 2009; Simpson et al. 2012; Mathivanan et al. 2012).”
• Mechanisms of mesenchymal stem/stromal cell function (2016, background): “, CD9, CD81), Alix, a calcium-binding protein with roles in both endosomal trafficking and cell death, and TSG101, a tumor suppressor protein [156, 157].”
• Exosomes: secreted vesicles and intercellular communications (2011, methodology): “Proteomic analyses of exosome composition were first performed on exosomes secreted by dendritic cells [10,11], and then on exosomes from numerous other different cell types, which are compiled in the ExoCarta compendium [12].”
• Using exosomes, naturally-equipped nanocarriers, for drug delivery (2015, background): “Recent studies have shown that they are specialized in long-distance intercellular communications [40,41] facilitating transfer of proteins [42,43], and functional mRNAs and microRNAs for subsequent protein expression in target cells [44,45].”
• Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses (2011, background): “(12)], confirmed that exosomes represent a specific subcellular compartment and are not random cell debris.”
• SORTING IT OUT: REGULATION OF EXOSOME LOADING (2014, background): “Anexin-2 is another protein that might play a role in RNA sorting into exosomes, since it is able to bind specific RNAs [67-69] and it is highly abundant in exosomes [70].”
• Bovine milk-derived exosomes for drug delivery (2015, methodology): “Exosome protein lysates were prepared and verified with western blot analysis for vital exosomal membrane markers CD63, CD81, transpanins, Tsg101 and alix [23, 24] (Fig.”
• Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers (2020, background): “Despite the public availability of several EVP protein databases, (e.g., Vesiclepedia, EVpedia, ExoCarta) (Kalra et al., 2012; Kim et al., 2015; Mathivanan and Simpson, 2009), much remains unknown about EVP proteomes, including: (1) markers for reliable isolation of EVPs in humans, regardless of tis”
• Exosomes in Cancer Development, Metastasis and Drug Resistance: A Comprehensive Review (2013, neutral): “org/, a database for exosome target identification and function) lists 4,563 proteins, 1,639 mRNAs, and 764 miRNAs as export targets of exosomes collected from 146 published studies on the Web [63, 64].”