Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

By A. Bobrie, Marina Colombo, G. Raposo, C. Théry. Traffic : the International Journal of Intracellular Transport, 2011

1,076 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a58773dcd4fb61988115315dfe72896596b59cb9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. C. Théry
2. Marina Colombo
3. A. Llorente
4. G. Raposo
5. Richard J. Simpson
6. T. Skotland
7. K. Sandvig
8. David W. Greening

In Molecular Biology

1. C. Théry
2. G. Raposo
3. Marina Colombo
4. Richard J. Simpson
5. A. Llorente
6. Guillaume van Niel
7. David W. Greening
8. J. Kowal

Citations in the corpus

• Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. (2014, background): “13g/ml for B cell exosomes [25] to 1.”
• Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth (2012, neutral): “There is considerable interest in using exosomes in clinical applications as biomarkers and/or as potential therapeutic tools [5, 60].”
• Tetraspanins in Extracellular Vesicle Formation and Function (2014, background): “Alternatively, some MVBs may fuse with the plasma membrane of the cell releasing ILVs as exosomes (1, 8).”
• Exosomes and their roles in immune regulation and cancer. (2015, background): “[116] Bobrie A, Colombo M, Raposo G, Thery C.”
• Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes (2019, background): “Exosomes are involved in a variety of functions, such as the eradication of obsolete molecules [25]; antigen presentation [26]; tumor progression, by promoting angiogenesis and tumor cell migration during metastases [27,28]; differentiation of regulatory T lymphocytes or myeloid cells to suppress im”
• Classification, Functions, and Clinical Relevance of Extracellular Vesicles (2012, background): “…evidence that the ESCRT is involved in the sorting of transmembrane receptors to intraluminal vesicles that are predestined to become secreted as exosomes (Théry et al., 2001; Buschow et al., 2005, 2009; Trajkovic et al., 2008; Simons and Raposo, 2009; Tamai et al., 2010; Bobrie et al., 2011).”
• Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles (2013, background): “Some MVBs are fated for degradation, whereas others can fuse with the plasma membrane, leading to the secretion of ILVs as exosomes (Bobrie et al., 2011; Raposo and Stoorvogel, 2013).”
• Exosomes and other extracellular vesicles in host–pathogen interactions (2014, neutral): “Thus, exosomes have been evaluated for the potential treatment of autoimmune diseases (Fig 2), a topic that has recently been the subject of several excellent reviews [75,103,104].”