Ecological and evolutionary forces shaping microbial diversity in the human intestine.

By Ruth E. Ley, D. Peterson, Jeffrey I. Gordon. Cell, 2006

3,305 citations recorded by the source corpus.

Subfields: Food Science, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6266b44b68b3456c73b2dd89d3f941a45dcedc11

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Citations in the corpus

Infectious diseases in wildlife: the community ecology context (2007, background): “org in the human microbiota, especially in the intestinal tract, can lead to an increased incidence of some diseases (Blaser 2006; Ley et al. 2006).”
Bile Acids and the Gut Microbiome (2014, background): “Bacterial 16S rRNA genes sharing 97–99% identity are referred to as an operational taxonomic unit (OTU) and represent a ‘phylotype’ [5].”
Homeostatic immunity and the microbiota (2017, neutral): “With an estimated composition of 100 trillion cells, microbes colonizing humans outnumber host cells and express more unique genes than their host’s genome (Ley et al., 2006).”
IgA response to symbiotic bacteria as a mediator of gut homeostasis. (2007, background): “How do perturbations in microbial ecology contribute to certain pathologic states such as infectious diarrheas, inflammatory bowel diseases, and metabolic abnormalities, for example (Frank et al., 2007; Ley et al., 2006b; Turnbaugh et al., 2006)?”
The microbial metabolites, short chain fatty acids, regulate colonic Treg cell homeostasis (2013, background): “Humans and mice rely on bacteria to breakdown undigestible dietary components, such as fibers (8).”
Synbiotic as Feed Additives Relating to Animal Health and Performance (2016, background): “The gastrointestinal tract which places a huge microbial ecosystem; the colon alone is estimated to contain over seventy percentage of all the microbes in the body [36] [37].”
Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation. (2006, background): “The bacteria that colonize the gastrointestinal tract are derived from the environment but selected for their ability to survive within this niche (Ley et al., 2006; Mackie et al., 1999).”
A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy (2012, background): “Primate fetal development is thought to occur within an intrauterine microbiota-free environment, and yet within a short interval following birth the human microbiome is colonizes and ‘‘differentiates’’ until the adult complement of 90 trillion or so microbiota is achieved [1,4,7,9].”
Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea (2009, background): “These bacteria are well-known dominant members of human fecal microbiota,(16) and these phyla are thought to play major ecologic roles in establishment and maintenance of gut homeostasis.(30) A lack of Bacteroides sp.”
Role of intestinal microbiota and metabolites on gut homeostasis and human diseases (2017, background): “Background Human gastrointestinal tract is known to host trillions of microbes [1, 2], the number of which reaches approximately 10(14) cells in the entire gut of a healthy individual [1].”
Probiotics and the gut microbiota in intestinal health and disease (2010, background): “Colonization and diversity Humans are naturally colonized at birth with microorganisms that inhabit the skin, oral cavity, vagina and gastrointestinal tract”
Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation (2010, background): “Thus, there has been and continues to be selection for mutualism between the microbiota and its host (2, 3).”