Biofilms in chronic wounds

By G. James, E. Swogger, R. Wolcott, E. Pulcini, Patrick R. Secor, Jennifer Sestrich, J. Costerton, P. Stewart. Wound Repair and Regeneration, 2008

1,482 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Rehabilitation

View Paper: https://www.semanticscholar.org/paper/c9c380c6f1842480fd3f2f442682ed05e677e2e8

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Citations in the corpus

Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration (2020, background): “Chronic wounds exhibit a persistent inflammation phase, resulting in microorganism recruitment, biofilm development [20], and the release of platelet-derived factors, such as transforming growth factor-beta (TGF-β), or ECM fragment molecules.”
Acute and Impaired Wound Healing: Pathophysiology and Current Methods for Drug Delivery, Part 1: Normal and Chronic Wounds: Biology, Causes, and Approaches to Care (2012, background): “Bacteria that colonize chronic wounds often form polymicrobial communities called biofilms.(61) These complex structures are composed of microbial cells embedded in secreted polymer matrix, which provides optimal environment for bacterial cell survival, enabling their escape from host immune surveil”
ESCMID guideline for the diagnosis and treatment of biofilm infections 2014. (2015, background): “For others such as chronic wounds [9,39,40] and tissue fillers [19],”
Wound repair and regeneration: Mechanisms, signaling, and translation (2014, neutral): “These microbial communities are believed to exist predominantly in the form of a biofilm (166), the composition of which depends on the type of chronic wound; the most prevalent genera in chronic wounds are Staphylococcus, Pseudomonas, and Corynebacterium.”
Inflammation in Chronic Wounds (2016, background): “Bacteria that colonise chronic wounds often form polymicrobial biofilms, in contrast to a minimal incidence within acute wounds [66].”
Bacterial Biofilm and its Role in the Pathogenesis of Disease (2020, background): “They found that as many as 60% of chronic wounds contained biofilm, as opposed to only 6% of acute wounds [111].”
The role of bacterial biofilms in chronic infections (2013, background): “(217) Soft tissue fillers FISH VII Otitis media FISH FISH Hall-Stoodley et al.”
Survey of bacterial diversity in chronic wounds using Pyrosequencing, DGGE, and full ribosome shotgun sequencing (2008, background): “Chronic wounds and their associated pathogenic biofilms [20,22,24,39-44] are also associated as a primary contributing factor in hundreds of thousands of annual deaths and billions of dollars in direct medical costs annually [20,22,38,45-55].”
Polymicrobial Interactions: Impact on Pathogenesis and Human Disease (2012, background): “A smaller-scale study using DGGE, 16S rRNA gene sequencing techniques, and microscopy to examine debrided tissues from diabetic foot wounds resulted in the identification of highly polymicrobial communities and the detection of several species unidentifiable by standard culturing techniques (98).”