Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.

By Lixin Sun, A. Hui, Q. Su, A. Vortmeyer, Yuri Kotliarov, S. Pastorino, A. Passaniti, Jayant P. Menon, Jennifer Walling, R. Bailey and 3 more. Cancer Cell, 2006

864 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c82307080ae5222f0162b5bfa078d92865e39fcc

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In Developmental Neuroscience

Richard J. Gilbertson

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In Molecular Biology

Citations in the corpus

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. (2010, result): “There was an overlap with downregulated genes in low- and intermediate-grade glioma compared to GBM in a variety of previously published data sets (Ducray et al., 2008; Liang et al., 2005; Sun et al., 2006) (Figure S5 and Table S3).”
A perivascular niche for brain tumor stem cells. (2007, background): “For example, KIT ligand (also known as stem cell factor), which is a potent glioma-derived proangiogenic factor (Sun et al., 2006), also promotes the migration, survival, and proliferation of neural progenitor cells (Erlandsson et al.”
An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1 (2010, methodology): “To verify class signatures in independent samples, expression profiles of GBM samples from 260 patients were collected from four published studies that used the HG-U133A or HG-U133plus2 GeneChip platforms (Beroukhim et al., 2007; Murat et al., 2008; Phillips et al., 2006; Sun et al., 2006).”
MEF promotes stemness in the pathogenesis of gliomas (2012, neutral): “A search conducted in the Oncomine website (https://www.oncomine.org//) revealed that in the Sun data set (Sun et al., 2006 To confirm these data we analyzed MEF expression by qPCR in 25 human glioma surgical samples from Memorial Sloan-Kettering Cancer Center (MSKCC) (six oligodendrogliomas, seven…”
Rembrandt: Helping Personalized Medicine Become a Reality Through Integrative Translational Research (2009, background): “4A is an expression heat map of 50 additional genes that have expression patterns related to stem cell factor (14) in glioblastoma multiforme.”
Comprehensive genomic characterization defines human glioblastoma genes and core pathways (2008, neutral): “Alfred Yung(11), Oliver Bogler(12), University of California San Francisco: Scott VandenBerg(9), Mitchel Berger(51), Michael Prados(51)”
Discriminative Least Squares Regression for Multiclass Classification and Feature Selection (2012, background): “In addition, the details about 6 Available at http://www.ics.uci.edu/ mlearn/MLRepository.html. the datasets of CLL-SUB-111 [55], GLA-BRA-180 [56], and TOX-171 7 can be found in Table IV.”
Angiogenesis in brain tumours (2007, background): “SCF is expressed in glioma cells and may have a role in tumour-induced angiogenesis in the brai”
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures (2016, background): “[45, 46] and c-Kit [47–49], for the heterogeneously infiltrated group (q < 0.”
MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators (2008, background): “In GBM/glioma progression, both STAT3 and Hif1a, a major mediator of cell response to hypoxia, are upregulated (47, 52) and can possibly account for miR-21 overexpression.”
Feature Selection Based on Structured Sparsity: A Comprehensive Study (2017, methodology): “We still cannot get the results of UDFS for the data set GLA even 7The process of tenfold cross validation is described here.”