D(1) receptors in prefrontal cells and circuits.

By Patricia S. Goldman-Rakic, E. Muly, Graham V. Williams. Brain research. Brain research reviews, 2000

853 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/c7e43655c685e19f21ce5cee59f62114e6d8a8f1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. E. T. Rolls
2. Gustavo Deco
3. E. Nestler
4. Andreas Nieder
5. Torben Ott
6. Michael J Frank
7. Georg Winterer
8. Trevor W. Robbins

In Endocrine and Autonomic Systems

1. E. Nestler
2. E. T. Rolls

In Experimental and Cognitive Psychology

1. E. Nestler
2. E. T. Rolls
3. Gustavo Deco
4. Trevor W. Robbins
5. Andreas Nieder
6. Morten L. Kringelbach
7. Kent C. Berridge

Citations in the corpus

• Computational models of schizophrenia and dopamine modulation in the prefrontal cortex (2008, background): “There is an inverted-U-shaped relationship between dopamine receptor activation and working-memory performance, in that excessive D1 receptor stimulation is as detrimental to cognitive performance as insufficient D1 receptor activatio”
• The mesolimbic dopamine reward circuit in depression. (2006, background): “…innervation from VTA dopamine neurons, where dopaminergic transmission has been shown to profoundly affect the functioning of these regions in electrophysiological and behavioral paradigms (e.g., see Goldman-Rakic et al 2000; Louilot and Besso 2000; Pezze and Feldon 2004; Wittmann et al 2005).”
• The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort. (2009, background): “…consistent with the well-established hypothesis of an inverted U-shaped curve relating prefrontal dopaminergic activity and executive performance (Goldman-Rakic et al., 2000), and suggest that Parkinson’s disease patients move from right to left on this puta- tive curve as their disease…”
• Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. (2003, background): “…stimulation and working memory performance where a high level of DA that enhances the glutamatergic inputs to both pyramidal cells and interneurons induces a depression of pyramidal cell activity by feed forward inhibition and an impairment of working memory function (Goldman-Rakic et al., 2000).”
• The principal features and mechanisms of dopamine modulation in the prefrontal cortex. (2004, background): “Preferential modulation of these interneurons in defined PFC microcircuits by DA might allow greater or lesser activiation between and within ‘‘memory fields’’ (Goldman-Rakic et al., 2000; Rao et al., 2000; Constantinidis et al., 2002).”
• Dopamine and Cognitive Control in Prefrontal Cortex. (2019, background): “It in fl uences processes such as working memory [12 – 15], attention [16,17], and fl exible behavior [18 – 20] that depend on the PFC [1].”
• Extraordinary neoteny of synaptic spines in the human prefrontal cortex (2011, background): “These data led to the hypothesis that an increase in dopaminergic innervation in the prefrontal cortex is associated with an increase in modulation of glutamatergic synapses located on the dendritic spine and involved in synaptic stabilization (65).”
• An opportunity cost model of subjective effort and task performance (2013, neutral): “There are direct projections from dopaminergic neurons to the lateral prefrontal cortex, and classic studies from Goldman-Rakic and colleagues (Goldman-Rakic 1996; Goldman-Rakic et al. 2000) demonstrate that the stability of prefrontal activity is a function of local dopamine levels.”