Lateral gene transfer and the nature of bacterial innovation

By Howard Ochman, Jeffrey G. Lawrence, E. Groisman. Nature, 2000

3,847 citations recorded by the source corpus.

Subfields: Ecology, Endocrinology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c5fdd14e897368dc5460478798680b6fb407b2aa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

In Endocrinology

In Molecular Biology

Citations in the corpus

Natural conjugative plasmids induce bacterial biofilm development (2001, background): “, which promotes the horizontal transfer of genetic material between donor and recipient cells by physical contact, is a phenomenon of fundamental evolutionary consequenc”
The quality of organic matter shapes the functional biogeography of bacterioplankton across boreal freshwater ecosystems (2015, background): “Regardless of the reasons for this apparent uncoupling between composition and function (e.g. dormancy, lateral gene transfer, functional redundancy; Ochman et al., 2000; Allison & Martiny, 2008; Jones & Lennon, 2010), there is a clear need to go beyond a taxonomic characterization of communities an”
Microbial horizontal gene transfer and the DNA release from transgenic crop plants (2005, background): “Gene transfer and recombination are recognized as adaptive strategies of microorganisms with evolutionary potential (Arber, 2000; Ochman et al., 2000).”
Gut microbiota modulation of chemotherapy efficacy and toxicity (2017, positive): “Firstly, as it is possible that given bacteria might transmit antibiotic resistance through horizontal gene transfer 98 , it is equally possible that chemotherapeutic resistance might be transmitted in a similar fashion, for example, through the transfer of β -glucuronidase or pyrimidine…”
Inference of Bacterial Microevolution Using Multilocus Sequence Data (2007, background): “(e.g. Dingle et al., 2005) or even genera ( Ochman et al., 2000 ), making the standard assumption”
Emerging pathogens: the epidemiology and evolution of species jumps (2005, background): “The mechanism of genetic change of the pathogen is also likely to be important: if it can evolve not only by mutation, but also by recombination (e.g. influenza viruses and SARS coronavirus [32, 43] ) or by gene capture (e.g. pathogenicity islands or antimicrobial resistance genes in bacteria [44, 4”
Life is Physics: Evolution as a Collective Phenomenon Far From Equilibrium (2010, background): “Microbes are able to exchange genes (horizontal gene transfer)[4], communicate between cells (quorum sensing)[5], translocate collectively over surfaces (swarming motility)[6, 7], and form biofilms—spatially-extended multicellular colonies with coordinated division of labor, cellular differentiation”
Prokaryotic evolution in light of gene transfer. (2002, background): “Barriers to homologous (legitimate) recombination do not preclude its occurrence—even between very distantly related organisms—because numerous illegitimate means are available for integrating foreign DNA into the genome (Ochman, Lawrence, and Groisman 2000).”
Genomic islands: tools of bacterial horizontal gene transfer and evolution (2008, background): “Whether encoding genes are involved in pathogenicity or biodegradation, GEIs can facilitate evolution by ‘quantum leaps’ as their acquisition or loss can rapidly and dramatically alter the life-style of a bacterium (Groisman & Ochman, 1996; Ochman et al., 2000; van der Meer & Sentchilo, 2003; Vernik”
Pathogenicity Islands in Bacterial Pathogenesis (2004, background): “The balance between selective gene acquisition and secondarily imposed gene loss implies that addition of a foreign gene increases the probability of loss of some resident function of lower selective value (207, 260).”
The role of hybridization in evolution (2001, background): “Gene exchange between bacterial species is common (Ochman et al. 2000), and can be detected because the hybridizing species are so divergent.”
How Do Species Interactions Affect Evolutionary Dynamics Across Whole Communities (2015, background): “Horizontal gene transfer (HGT) is a well-known mechanism for acquiring new functions in microbes (Ochman et al. 2000).”
Multidrug Resistance in Bacteria (2009, background): “Finally, it should be emphasized that conjugational transfer of plasmids is not a novel mechanism invented for multidrug resistance; indeed, horizontal transfer of genes, to a large extent through the conjugational mechanism, has been the main mechanism used for the evolution of many groups of bacte”
Origins of bacterial diversity through horizontal genetic transfer and adaptation to new ecological niches. (2011, background): “With eventual access to genome sequences, it became clear that HGT occurs throughout the genome, and has been responsible for the origins of extremely diverse adaptations (Ochman et al., 2000).”
Studying plasmid horizontal transfer in situ: a critical review (2005, background): “In bacteria, the presence of intergenomic variation can be interpreted as an illustration that HGT contributes profoundly to genetic diversity and evolutio”
IslandPath: aiding detection of genomic islands in prokaryotes (2003, background): “coli, to none identified to date in some obligate intracellular species such as Rickettsia and Chlamydia (Ochman et al., 2000).”