Milestones of neuronal development in the adult hippocampus.

By Gerd Kempermann, Sebastian Jessberger, B. Steiner, Golo Kronenberg. Trends in Neurosciences, 2004

1,516 citations recorded by the source corpus.

Subfields: Cancer Research, Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/c5930a6a0b781227b1184b84041d81fd999514d1

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Citations in the corpus

Structural Plasticity and Hippocampal Function (2010, background): “Neurogenesis in the adult brain is a complex process characterized by distinct milestones (reviewed in Kempermann et al. 2004).”
Type‐2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis (2006, methodology): “GLIA DOI 10.1002/glia The present data strengthen the initial concept (Kempermann et al., 2004) and add further distinctive criteria to the important transitional phase between the precursor cells and neuronal development, which is captured by the category type-2b.”
Reversible effect of X‐irradiation on proliferation, neurogenesis, and cell death in the dentate gyrus of adult mice (2007, positive): “Slowly dividing precursor cells maintain adult hippocampal neurogenesis (AhN) in the dentate gyrus and give rise to rapidly proliferating neuronal progenitors (reviewed in Kempermann et al., 2004).”
Stage-Specific Functions of the Small Rho GTPases Cdc42 and Rac1 for Adult Hippocampal Neurogenesis (2013, methodology): “To characterize the expression pattern of Cdc42 and Rac1 in the adult DG, we costained brain sections for Rac1 and Cdc42 together with stage-specific markers of neurogenesis (Kempermann et al., 2004).”
Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration. (2014, background): “Similar to the SVZRMS, polySia-positive neuroblasts are generated from astrocytic stem cells in this second major neurogenic niche of the adult brain (121, 229).”
Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis (2010, background): “Prox1 Is Required for the Maintenance of Intermediate Progenitors in the SGZ During Adult Neurogenesis In the SGZ, Prox1 expression is initially detected in Tbr2 (Figure 6E) [35] and Dcx (Figure 6F) Type-IIb intermediate progenitors [36] and is absent from adult NSCs (Figure 6A,B,C) [37,38] and Ascl”
RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus (2010, background): “The Sox2-expressing stem cell population in the SGZ consists of quiescent or slowly dividing multipotent stem cells with a radial glia-like morphology (type 1 cells) and of nonradial stem/precursor cells (type 2 cells), which show higher levels of proliferation (Kempermann et al., 2004; Suh et al., ”
Potential role for adult neurogenesis in the encoding of time in new memories (2006, background): “For how long would this time association occur within the sparse codes produced by the dentate gyrus? The maturation of newborn neurons takes approximately 1 to 2 months in rodent”
Delayed Development of Adult-Generated Granule Cells in Dentate Gyrus (2006, background): “It is generally acknowledged that adult neurogenesis occurs in a relatively hostile environment (Kempermann et al., 2004; Rakic, 2004).”
Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF-κB p50-Deficient Mice (2008, background): “To further dissect the steps of neuronal differentiation that could be under the control of NF- B p50, we also examined newly generated neuronal cells in postmitotic stages, when recruitment for terminal differentiation takes place (Kempermann et al., 2004).”
The Chemokine Stromal Cell-Derived Factor-1 Regulates GABAergic Inputs to Neural Progenitors in the Postnatal Dentate Gyrus (2008, background): “Neural stem cells residing in the subgranular zone (SGZ) of the adult hippocampal dentate gyrus (DG) generate new granule neurons throughout life (Kempermann et al., 2004; Zhao et al., 2006).”
Modification of hippocampal circuitry by adult neurogenesis (2012, background): “Adult hippocampal neurogenesis is a complex, multistep process that is highly regulated by existing neuronal network activity (Kempermann et al., 2004; Ma et al., 2009; Ming and Song, 2011).”
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. (2009, background): “Newborn granule cells pass through several developmental steps, from a dividing progenitor to a mature granule cell that becomes indistinguishable from granule cells born during embryonic development (Kempermann et al. 2004; Laplagne et al. 2006; Suh et al. 2007).”