Caspase activation: Stepping on the gas or releasing the brakes?

By G. Salvesen. 2005

255 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/c47de7e98026e66fa387daf26b14dae27cddd1dd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. J. Martinou
2. R. Youle
3. D. C. Chan
4. Douglas R. Green
5. J. Nunnari
6. Jerry M. Adams

Citations in the corpus

• Mitochondria in Apoptosis: Bcl-2 family Members and Mitochondrial Dynamics (2011, background): “The Role of Mitochondria in Drosophila Cell Apoptosis Steps of apoptosis upstream of caspases are regulated differently in flies and mammals (Salvesen and Abrams, 2004).”
• Cisplatin in cancer therapy: molecular mechanisms of action (2014, unknown): “Initiator caspases include caspases 8 and 9, and activation of these caspases results in activation of downstream or executioner caspases such as caspases 3 and 7 (Salvesen and Abrams, 2004).”
• REACTIVE OXYGEN SPECIES, CELLULAR REDOX SYSTEMS AND APOPTOSIS (2010, unknown): “Caspases are constitutively expressed as monomers in the cytosol as inactive zymogen, and are activated by apoptotic signals such as ROS via proteolysis at internal sites [206].”