Mechanisms and functions of p38 MAPK signalling.

By A. Cuadrado, A. Nebreda. Biochemical Journal, 2010

1,629 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c4148ebffd8f247eaa8b7e8b549901b2cecbaba9

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In Cell Biology

1. Philippe P Roux
2. R. Davis
3. G. Sabio

In Molecular Biology

1. G. Sabio
2. Philippe P Roux
3. R. Davis
4. Marie Cargnello
5. David M. Sabatini
6. R. Seger

Citations in the corpus

• Controlling gene expression in response to stress (2011, background): “For example, the SAPKs in mammals are the p38 mitogen-activated protein kinase (MAPK) family (which contains four isoforms, MAPK11–14); these signalling pathways are activated by a variety of environmental (physical and chemical) stresses, such as heat shock, ultraviolet light, gamma rays, anisomyci”
• TNF and MAP kinase signaling pathways (2014, positive): “The p38δ MAP kinase is highly expressed in a limited number of tissues, including neutrophils and endocrine glands [20, 64, 91, 92].”
• Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways? (2011, background): “Several MAP3Ks have been shown to trigger p38 MAPK activation, and they include ASK1 (apoptosis signal-regulating kinase 1), DLK1 (dual-leucinezipper-bearing kinase 1), TAK1 (transforming growth factor β-activated kinase 1), TAO (thousand-and-one amino acid) 1 and 2, TPL2 (tumor progression loci 2),”
• p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents. (2014, background): “p38 MAPK plays an important role in the regulation of apoptosis, cell cycle arrest, growth inhibition and differentiation [19].”
• Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases (2011, background): “MKK3/6 are activated by a plethora of MAPKKKs, including MEKK1 to -3, MLK2/3, ASK1, Tpl2, TAK1, and TAO1/2 (76).”
• ROS and ROS-Mediated Cellular Signaling (2016, neutral): “p38 pathway [68, 69].”