Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

By Marie Cargnello, Philippe P Roux. Microbiology and Molecular Reviews, 2011

2,966 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies (2023, methodology): “60 Including the cytoplasmic substrates death-associated protein kinase (DAPK), tuberous sclerosis complex 2, RSK, and MNK, and the nuclear transcription factor substrates nuclear factor of activated T cells (NF-AT), Elk-1, myocyte enhancer factor 2 (MEF2), c-Fos, c-Myc, and signal transducer and…”
Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer (2021, background): “MAPK signaling pathways comprises signaling cascades involving three major kinases: ERK, c-Jun-N-terminal kinase (JNK), and p38 (MAPK14).(154,155) Components of the MAPK pathways respond to various input signals, including cytokines, chemokines, growth factors, and stress, etc.”