In vitro toxicity of nanoparticles in BRL 3A rat liver cells.

By Saber M. Hussain, K. Hess, J. Gearhart, K. Geiss, John J. Schlager. Toxicology in Vitro, 2005

2,064 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Materials Chemistry, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/c3bbe51295a40a1b0cbd38b84eb1365a21771a39

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In Health, Toxicology and Mutagenesis

In Materials Chemistry

In Public Health, Environmental and Occupational Health

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Citations in the corpus

The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells. (2008, background): “(Hussain et al., 2005) but greater than that reported formammalian spermatogonial stem cells (Braydich-Stolle et al.”
Molecular Toxicity Mechanism of Nanosilver (2014, background): “[105] Hussain SM, Hess KL, Gearhart JM, et al.”
Nanotoxicity of iron oxide nanoparticle internalization in growing neurons. (2007, background): “[25] presented data on the effects that various metal/metal oxide nanomaterials had upon liver cell function in vitro.”
DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells. (2008, background): “Previously it was reported that Ag NPs reduce mitochondrial function and increase membrane leakage in mammalian germline stem cells and increase reactive oxygen species (ROS) generation, deplete antioxidant GSH content, and reduce mitochondrial function in BRL 3A rat liver cells (Braydich-Stolle et ”
Anti-proliferative activity of silver nanoparticles (2009, background): “Moreover, Ag-nps were reported to act via reactive oxygen species (ROS) production and glutathione depletion in rat liver cells [12].”
Silver nanoparticles in simulated biological media: a study of aggregation, sedimentation, and dissolution (2011, background): “However, other reports indicate that Ag nanoparticles can be toxic to cells even at 10 mg/L ( Hussain et al. 2005 ).”
Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects (2012, background): “In one study, in vitro toxicity assay of silver nanoparticles in rat liver cells has shown that even low-level exposure to silver nanoparticles resulted in oxidative stress and impaired mitochondrial function [79].”
Nanodiamond Particles: Properties and Perspectives for Bioapplications (2009, neutral): “227 , 228 , 229 , 230 To fully assess the life cycle impact of nanoparticles, from synthesis to disposal, the new sub-field of ‘nanotoxicology’ was coined in 2004.”
Effect of silver on burn wound infection control and healing: review of the literature. (2007, background): “[18] Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ.”