Intracellular signalling controlling integrin activation in lymphocytes

By T. Kinashi. Nature reviews. Immunology, 2005

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Immune cell migration in inflammation: present and future therapeutic targets (2005, background): “The molecular basis of integrin activation underlying leukocyte stoppage (sticking and arrest) on target endothelial sites is beginning to unfol”
Activation, coactivation, and costimulation of resting human natural killer cells (2006, background): “Many signaling molecules and pathways have been implicated in modulation of LFA-1 affinity (115).”
Getting to the site of inflammation: the leukocyte adhesion cascade updated (2007, background): “However, recent evidence suggests that additional steps occur during integrin-mediated leukocyte adhesion, which remain incompletely understoo”
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer (2009, background): “We therefore tested whether fibrillar β-amyloid peptide (1-42) (Aβ1-42) could activate TLR4-TLR6 signaling via CD36.”