Changes in emotion after circumscribed surgical lesions of the orbitofrontal and cingulate cortices.

By J. Hornak, J. Bramham, E. T. Rolls, R. Morris, John P. O'Doherty, P. Bullock, C. Polkey. Brain : a journal of neurology, 2003

733 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/c0a3ceb8d6e7661283d3c5e67db80a51e781bacb

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In Cognitive Neuroscience

Citations in the corpus

A meta-analytic review of emotion recognition and aging: implications for neuropsychological models of aging. (2008, background): “Less is known about individual emotions, although angry, sad and unpleasant sounds involve the OFC (Hornak et al., 2003; Sander et al., 2005) and amygdala (Scott et al., 1997), and fear sounds involve the amygdala (Morris et al., 1999; Scott et al., 1997; although see Pourtois et al., 2005) and insu”
Synaptic and spiking dynamics underlying reward reversal in the orbitofrontal cortex. (2004, background): “…rapidly to changing reinforcement contingencies produced by damage to brain regions such as the orbitofrontal cortex may be related to the emotional and behavioural changes that follow alteration of the function of these regions (Damasio, 1994; Rolls et al., 1994; Hornak et al., 2003, 2004).”
Emotion and attention interactions in social cognition: Brain regions involved in processing anger prosody (2005, positive): “Patients with focal OFC lesions are impaired in personal and social decision-making, and exhibit amodal deficits in the processing of facial and vocal emotional expressions (Damasio, 1994; Hornak et al., 1996, 2003).”
The experience of emotion. (2007, background): “2004); individuals with bilateral OFC lesions report large alterations in emotion experience (Hornak et al. 2003).”
Emotion and the Prefrontal Cortex: An Integrative Review (2017, background): “Human patients with lesions of the pgACC (extending into sgACC and DMPFC) exhibit significant changes in the intensity and frequency of subjective feelings (Hornak et al., 2003).”
Neuroscientific Evidence for Simulation and Shared Substrates in Emotion Recognition: Beyond Faces (2009, background): “The authors posit that vocal prosody is a more sensitive test of emotion recognition ability than facial expressions because it is less easily translated into verbalizable cues (Hornak et al., 2003).”
Neural correlates of rapid reversal learning in a simple model of human social interaction (2003, background): “On the basis of human lesion studies it has been proposed that the orbitofrontal cortex is crucial for controlling affective responses to salient emotional stimuli (Damasio, 1994; Davidson et al., 2000; Hornak et al., 1996, 2003a; Rolls, 1999; Rolls et al., 1994).”
The neuroimaging of emotion. (2008, background): “Damage to OFC is associated with inappropriate generation and regulation of affect, which may take the form of flattened affect, increased expression and reports of negative emotion, or inappropriate emotion given the social context, depending on the case (Beer, Heerey, Keltner, Scabini, & Knight, 2”
To What Extent is the Experience of Empathy Mediated by Shared Neural Circuits? (2010, background): “So far, neuropsychological studies have documented a critical role of the medial and orbitofrontal cortex, closely interconnected with the amygdala, in social emotions, including empathy and sympathy (e.g., Hornak et al., 2003; Shamay-Tsoory, 2009).”
Dissecting the Neural Mechanisms Mediating Empathy (2011, background): “…regions involved in the mirror neuron system (ventral premotor, motor cortex and anterior IPS) leads to any dysfunction in empathy, sympathy or moral reasoning, whereas lesions of the ventromedial prefrontal cortex are associated with such socio-cognitive disturbances (e.g., Hornak et al., 2003).”
What does the prefrontal cortex "do" in affect: perspectives on frontal EEG asymmetry research. (2004, background): “…fact and to indicate that the majority of the neuroscience literature indicates that the prefrontal sector most directly associated with emotion is the sector that is least likely to be reflected in scalp-recorded brain electrical signals—namely, orbital frontal cortex (e.g.,Hornak et al., 2003).”
Identification of emotional intonation evaluated by fMRI (2005, background): “Moreover, patients suffering from unilateral circumscribed lesions to this area showed impaired identification of emotional face and voice expressions whereas performance in nonemotional control tasks (i.e., discrimination of unfamiliar voices and recognition of environmental sounds) was unimpaired ”
Finally, faces find favor (2006, background): “, 1997, 1999), as well as neural systems for processing reward, including the orbitofrontal cortex and the anterior cingulate cortex (Hornak, Rolls, & Wade,1996; Hornak et al., 2003; Rolls, 2004).”
Affective neuroscience of pleasure: reward in humans and animals (2008, background): “And while modern analyses of more focal prefrontal lesions report deficits in cognitive–emotional processing of decisions of human patients, they generally do not indicate a total loss of the capacity for pleasures (Bechara et al. 2000; Damasio 1999; Damasio 2004; Hornak et al. 2003).”
Reward-related Reversal Learning after Surgical Excisions in Orbito-frontal or Dorsolateral Prefrontal Cortex in Humans (2004, methodology): “Further, in a subjective emotional change questionnaire, in which the patients reported on any changes in the intensity and/or frequency of their own experience of emotions since surgery, the bilateral orbito-frontal cortex patients with deficits in the visual discrimination reversal task reported a”