Diffusion in Biofilms

By P. Stewart. Journal of Bacteriology, 2003

1,191 citations recorded by the source corpus.

Subfields: Condensed Matter Physics, Ecology, Evolution, Behavior and Systematics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/c0721d6ba6eca9bcfa418c9255e2c80780afaebc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Condensed Matter Physics

1. A. Decho
2. T. Gutierrez
3. R. Leng
4. M. Franklin

In Ecology, Evolution, Behavior and Systematics

1. A. Decho
2. T. Gutierrez
3. R. Leng
4. M. Franklin

In Molecular Biology

1. T. Gutierrez
2. A. Decho
3. M. Franklin
4. D. Lebeaux
5. C. Beloin
6. J. Ghigo
7. R. Leng
8. P. Stewart

Citations in the corpus

• Biofilms: At the Interface between Biophysics and Microbiology (2006, neutral): “driven mechanism [176].”
• Multimetal resistance and tolerance in microbial biofilms (2007, background): “It may be that the matrix impedes the diffusion and equilibration of small molecule”
• Interactions between microbial consortia in biofilms: a paradigm shift in rumen microbial ecology and enteric methane mitigation (2014, background): “Agriculture Organisation: Rome) Stewart PS (2003) Diffusion in biofilms.”
• Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance (2020, background): “architecture (Figure 1), the time for an antibiotic to reach the interior of the biofilm varies between strains [68].”
• Understanding the Mechanism of Bacterial Biofilms Resistance to Antimicrobial Agents (2017, background): “The level of bacterial growth and activity inside biofilm was proved by different concentration of metabolic substrates and products [16].”
• Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics (2014, background): “Many reports suggested that mechanical and physicochemical properties of the biofilm matrix can reduce or delay penetration of numerous compounds, including antibiotics and antiseptics (34, 35).”
• Physiological heterogeneity in biofilms (2008, background): “The biofilm matrix is an aqueous solution, and solutes that are the size of oxygen diffuse in the matrix at a rate that is approximately 60% of the diffusion rate in pure wate”
• Microbial Extracellular Polymeric Substances (EPSs) in Ocean Systems (2017, methodology): “A number of investigators have carefully measured diffusion rate constants by monitoring the movement of fluorescent molecules over time using confocal scanning laser microscopy and other approaches (Lawrence et al., 1994; Guiot et al., 2002; Stewart, 2002; De Beer et al., 2004; Waharte et al., 2010”
• Bacterial extracellular electron transfer in bioelectrochemical systems (2012, background): “Starvation and proton accumulation resulting from the low diffusion coefficiency in biofilms can strongly suppress the viability of the biofilm cells, especially for the bottom layers [78,93].”
• Biofilm Formation in Food Processing Environments is Still Poorly Understood and Controlled (2014, background): “Interestingly, among the genes differentially regulated in biofilms are those involved in metabolism or starvation responses [109].”