Age-related Changes in Brain Activity across the Adult Lifespan

By Cheryl L. Grady, Mellanie V. Springer, Donaya Hongwanishkul, Anthony Randal McIntosh, Gordon Winocur. Journal of Cognitive Neuroscience, 2006

501 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/c03c27d1f49b8fdcd3bc4676900cee6891443fbf

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Citations in the corpus

A Brain-Wide Study of Age-Related Changes in Functional Connectivity. (2015, background): “In several studies, it has been shown that older participants show reduced suppression of the DMN during performance of cognitive tasks (Lustig et al. 2003; Grady et al. 2006; Persson et al. 2007; Sambataro et al. 2010).”
Age Differences in Deactivation: A Link to Cognitive Control? (2007, background): “that both healthy aging and dementia are also associated with altered deactivations of the default-mode network (Grady et al., 2006; Rombouts, Barkhof, Goekoop, Stam, & Scheltens, 2005; Lustig et al., 2003).”
A meta-analytic review of emotion recognition and aging: implications for neuropsychological models of aging. (2008, background): “In fact, an increase in activation in medial frontal areas is seen in a range of tasks (e.g., memory tasks) not just emotion tasks, and is thought to indicate older adults’ greater difficulty suspending nontask-related ‘‘default-mode’’ neural activity (Grady, 2002; Grady et al., 2006).”
Reduced resting-state brain activity in the "default network" in normal aging. (2008, background): “tasks (Lustig et al. 2003; Grady et al. 2006), intrinsic activity”
Video game training enhances cognitive control in older adults (2013, methodology): “Using the analysis metrics regularly reported for each measure, we performed a mixed model ANOVA of Group (3: MTT, STT, NCC) X Session (2: pre, post) X Cognitive test (11; see Supplementary Table 2), and observed a significant 3-way interaction (F(20, 400)= 2.”
Que PASA? The posterior-anterior shift in aging. (2008, background): “It is worth noting that although the observed age-related attenuation in posterior deactivations are consistent with previous studies of healthy aging (Lustig et al. 2003; Grady et al. 2006; Persson et al. 2007), the location of this deactivation is also dorsal to regions shown to activate during su”
Cognitive Neuroscience of Aging (2008, background): “This taskrelated reduction of activity in default mode regions is smaller in older adults (Grady et al. 2006; Lustig et al. 2003).”