Age Differences in Deactivation: A Link to Cognitive Control?

By J. Persson, Cindy Lustig, James K. Nelson, Patricia A. Reuter-Lorenz. Journal of Cognitive Neuroscience, 2007

343 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/7c52e6041ba560859ab13e3cca4b924d2bbc478c

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In Cognitive Neuroscience

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Citations in the corpus

Cognitive Neuroscience of Aging (2008, neutral): “A third study used a different approach to studying cognitive control by focusing on default mode regions (Persson et al. 2007).”
The Adaptive Brain: Aging and Neurocognitive Scaffolding (2009, background): “The pervasive evidence in the functional brain-imaging literature of greater bilateral activation and overacti-vationoffrontalareasinolderadultsreﬂectsthe both declining networks and the associated compensatory circuitry recruited to meet the task demands.”
Transient and linearly graded deactivation of the human default-mode network by a visual detection task (2008, positive): “It has also been shown thatDMNdeactivation ismodulated in clinical populations, such as those with an autistic-spectrum disorder (Kennedy et al., 2006), schizophrenia (Garrity et al., 2007; Harrison et al., 2007) and the elderly (Persson et al., 2007).”
Plasticity of Brain Networks in a Randomized Intervention Trial of Exercise Training in Older Adults (2010, neutral): “For example, attenuated task-induced suppression of the DMN has been coupled to delayed over-activation in task-relevant networks (Persson et al., 2007).”
Que PASA? The posterior-anterior shift in aging. (2008, background): “It is worth noting that although the observed age-related attenuation in posterior deactivations are consistent with previous studies of healthy aging (Lustig et al. 2003; Grady et al. 2006; Persson et al. 2007), the location of this deactivation is also dorsal to regions shown to activate during su”
The Common Neural Basis of Autobiographical Memory, Prospection, Navigation, Theory of Mind, and the Default Mode: A Quantitative Meta-analysis (2009, neutral): “SITF Reading PET 6 1 ROI McKiernan, Kaufman, Kucera-Thompson, & Binder ( 2003 ) Rest Target detection fMRI 30 20 Persson, Lustig, Nelson, & Reuter-Lorenz ( 2007 ) Fixation Verb generation fMRI 60 11 32 young, 28 older adults Raichle et al.”
Frontocingulate Dysfunction in Depression: Towards Biomarkers of Treatment Response (2010, background): “…increases in cognitive load and task difficulty have been associated with increased activation of the TPN and greater deactivation of the DN (eg, McKiernan et al, 2003; Pallesen et al, 2009; Tomasi et al, 2006), including the rACC (Pallesen et al, 2009; Persson et al, 2007; Polli et al, 2005).”
A Brain-Wide Study of Age-Related Changes in Functional Connectivity. (2015, background): “In several studies, it has been shown that older participants show reduced suppression of the DMN during performance of cognitive tasks (Lustig et al. 2003; Grady et al. 2006; Persson et al. 2007; Sambataro et al. 2010).”