Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

By Harry Sokol, B. Pigneur, L. Watterlot, O. Lakhdari, L. Bermúdez-Humarán, J. Gratadoux, S. Blugeon, C. Bridonneau, J. Furet, G. Corthier and 10 more. Proceedings of the National Academy of Sciences of the United States of America, 2008

4,384 citations recorded by the source corpus.

Subfields: Epidemiology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bf07002d65ff1590fa0fccbc2b878d702507d540

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Citations in the corpus

Genetics and pathogenesis of inflammatory bowel disease (2011, background): “prausnitzii stimulates IL-10 production in peripheral blood mononuclear cells, which may account at least in part for this protective effec”
Mechanisms and consequences of intestinal dysbiosis (2017, background): “Also Faecalibacterium prausnitzii, which is less abundant in Crohn’s disease patients than in healthy subjects, exerts its antiinflammatory effects partially via the elevation of IL-10 production [146].”
The Cirrhosis Dysbiosis Ratio defines Changes in the Gut Microbiome Associated with Cirrhosis and its Complications (2013, neutral): “These taxa are also overrepresented in healthy controls in inflammatory bowel disease and irritable bowel syndrome [20,21].”
Natural history of the infant gut microbiome and impact of antibiotic treatments on strain-level diversity and stability (2015, background): “The opposite pattern was observed for two notable beneficial commensal bacteria (34, 35).”
Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene. (2010, background): “Commensal butyrate-producing bacteria appear to play a key role within the human colon, supplying energy to the mucosal cells and helping to maintain health through a variety of mechanisms (Pryde et al., 2002; Hamer et al., 2008; Sokol et al., 2008; Louis and Flint, 2009).”
Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe −/− Mice (2016, background): “nitzii, improves the survival rate of chemical-induced colitis in animals.(5) Conversely, higher proportions of Firmicutes and”
Probiotics in Food Systems: Significance and Emerging Strategies Towards Improved Viability and Delivery of Enhanced Beneficial Value (2019, background): “prausnitzii as a probiotic could modulate dysbiosis phenomena in the gut [38].”