Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe −/− Mice

By Jin Li, Shao-qiang Lin, P. Vanhoutte, C. W. Woo, A. Xu. Circulation, 2016

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Factors affecting the composition of the gut microbiota, and its modulation (2019, background): “…under dietary fiber deficiency causes the erosion of the colonic mucus barrier (Desai et al., 2016) and studies on experimental mice demonstrated that administration of Akkermansia muciniphila, mucin degrade, lead to restoration of the gut barrier (Everard et al., 2013; Li et al., 2016a).”
The gut microbiome: Relationships with disease and opportunities for therapy (2018, background): “Protects against atherosclerosis by decreasing gut permeability and preventing endotoxemia-induced inflammation (Li et al., 2016a) Improves efficacy of anti-cancer immunotherapy (Routy et al., 2018)”
Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila (2017, background): “It is worth noting that all these findings have subsequently been confirmed by different groups and extended to other specific disorders such as atherosclerosis, hepatic inflammation and hypercholesterolemia (Shin et al., 2014; Li et al., 2016; Shen et al., 2016; Grander et al., 2017; Plovier et al.”