Apoptotic pathways: ten minutes to dead.

By Douglas R. Green. Cell, 2005

800 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bd135ef6430bab7721eaaa0814c947e16f1cf773

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Citations in the corpus

Crosstalk between apoptosis, necrosis and autophagy. (2013, background): “In either case, activation of cysteine aspartyl proteases, called caspases, results in mitochondrial membrane permeabilization, chromatin condensation and DNA fragmentation, thereby leading to the destruction of the cell [4].”
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. (2009, neutral): “Caspases are cysteinyl aspartate proteases that function as apical initiators or distal effectors to orchestrate the apoptotic cell death program (Boatright et al., 2003; Green, 2005).”
Self-eating and self-killing: crosstalk between autophagy and apoptosis (2007, background): “Apoptosis is the best-described form of programmed cell death and involves the activation of catabolic enzymes — in particular proteases — in signalling cascades, which leads to the rapid demolition of cellular structures and organelle”
Mechanisms of cytochrome c release from mitochondria (2006, background): “Presumably, the same applies to BAK, although the latter resides in the OM also in its inactive state.(58) It has been proposed that BAK is”
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. (2006, background): “Within a short time, MOMP is followed by apoptosome formation and caspase activation resulting in apoptosis (Green, 2005).”
Caspases and their substrates (2017, methodology): “It is known that there is a significant time delay of a few hours prior to the induction of caspase activation in cells.(70,71) An extensive study of the transcriptional and translational events that precede induction of caspases in bortezomib-treated MM1S cells was conducted using RNAseq, ribosomal”