Programming by early nutrition in man.

By A. Lucas. Ciba Foundation symposium, 2007

944 citations recorded by the source corpus.

Subfields: Nutrition and Dietetics, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/bc9b8657d65ac518dd01994a32c008fe73b4a986

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Nutrition and Dietetics

In Pediatrics, Perinatology and Child Health

Citations in the corpus

Early life events and their consequences for later disease: A life history and evolutionary perspective (2007, background): “There is a considerable literature relating the nature of infant feeding to later health consequences (e.g., Lucas, 1991) and also relating birth size to later risk of disease (e.g., Syddall et al., 2005).”
Transposable Elements: Targets for Early Nutritional Effects on Epigenetic Gene Regulation (2003, background): “Human epidemiologic and animal model data indicate that susceptibility to adult-onset chronic disease is influenced by persistent adaptations to prenatal and early postnatal nutrition (1, 2, 13, 14); however, the specific biological mechanisms underlying such adaptations remain largely unknown.”
Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth (2004, background): “Thus the variable components of syndrome X, including defective beta-cell function, hypertension, hyperlipidaemia and insulin resistance may be programmed [ 30 ] by changes in the intrauterine and early infant environment.”
Evidence on the long-term effects of breastfeeding SYSTEMATIC REVIEWS AND META-ANALYSES (2007, background): “This idea originates from the more general concept in developmental biology which was defined by Lucas as “programming” (11).”
Life course health development: an integrated framework for developing health, policy, and research. (2002, background): “When an early environmental stimulus or insult occurs during a critical or sensitive period, it programs a long-term or permanent change in an organism’s functional system (Ben-Shlomo and Kuh 2002; Lucas 1991; Wadsworth 1999).”
Fetal origins of obesity. (2003, background): “Possible Mechanisms for an Association Between Birth Weight and Later Adiposity Research into the fetal origins of adult diseases generally relies on the assumption of programming, the process wherein a stimulus occurring at a critical period of development has lasting effect (54).”
Epigenetics and the embodiment of race: Developmental origins of US racial disparities in cardiovascular health (2009, background): “Researchers who attribute some, or all, of the problem of racial health inequalities to differences in genetic predisposition (Burchard et al., 2003; Hirsch et al., 2006; Risch et al., 2002; Sarich and Miele, 2004; Saunders, 1995) assume that human genetic variation can be differentiated into…”