Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice
By L. Kassar-Duchossoy, Barbara Gayraud-Morel, Danielle Gomès, D. Rocancourt, Margaret E. Buckingham, V. Shinin, S. Tajbakhsh. Nature, 2004
690 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/bc541e9dd625f80dca1c5610e4a18c8c91a36090
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- P. Zammit
- Michael A. Rudnicki
- C. Bentzinger
- F. Relaix
- T. Partridge
- Yu Xin Wang
- Thomas Braun
- Stephen J. Tapscott
Citations in the corpus
- Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells (2006, background): “Mrf4 is not detectable in adult satellite cells (unpublished data), although it is expressed when they differentiate (Cooper et al., 1999), and this gene does not play a role as a determination factor during late embryonic and fetal development (Kassar-Duchossoy et al., 2004, 2005).”
- The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, background): “Mrf4 acts only as amyogenic determination factor in embryonic cells (Kassar-Duchossoy et al. 2004), whereas myogenin is required only for differentiation before birth (Knapp et al. 2006).”
- Building muscle: molecular regulation of myogenesis. (2012, background): “Using a series of different Myf5 mutant alleles, it has been shown that the original knockin at the Myf5 locus also impaired the function of the neighboring MRF4 gene (Kassar-Duchossoy et al. 2004).”
- The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription (2005, background): “Recent studies indicate that Mrf4 has roles in both muscle specification and differentiation (Kassar-Duchossoy et al., 2004).”
- Satellite Cells and Skeletal Muscle Regeneration (2015, neutral): “Moreover, Pax3 has been shown to regulate the expression of Myf5 and MyoD in the embryos, which triggers myogenic determination (239).”
- A Pax3/Pax7-dependent population of skeletal muscle progenitor cells (2005, background): “In the absence of the myogenic regulatory factors MyoD, Myf5 and Mrf4 (ref”
- Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis (2011, background): “MRF4 seems to have a dual role: it is thought to be a differentiation gene acting in postmitotic maturating cells, but it is also expressed by undifferentiated proliferating cells in which it might act as a determination gen”