A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

By F. Relaix, D. Rocancourt, A. Mansouri, Margaret E. Buckingham. Nature, 2005

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View Paper: https://www.semanticscholar.org/paper/ce91e1ac2bebc21f347e310cd9111366d4fd2c61

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Citations in the corpus

Asymmetric self-renewal and commitment of satellite stem cells in muscle. (2007, result): “Recent experiments support this work and indicate that a significant proportion of the progenitors of satellite cells originate in embryonic somites as Pax3/Pax7-expressing cells (Ben-Yair and Kalcheim, 2005; Gros et al., 2005; Kassar-Duchossoy et al., 2005; Relaix et al., 2005; Schienda et al., 200”
The Skeletal Muscle Satellite Cell: The Stem Cell That Came in From the Cold (2006, background): “…from a variety of tissues including thymus (Pagel et al. 2000), nerve (Courbin et al. 1989), brain (Tajbakhsh et al. 1994; Galli et al. 2000; Rietze et al. 2001), and others (comprehensively reviewed in Grounds et al. 2002) have all been shown to generate skeletal muscle in vitro and, in…”
Making muscle: skeletal myogenesis in vivo and in vitro (2017, background): “These were progressively replaced by a pool of Pax7+ myogenic progenitors, as observed in vivo (Chal et al., 2015; Kassar-Duchossoy et al., 2005; Relaix et al., 2005).”
Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage (2012, positive): “Later, Pax7 is activated within these Pax3-expressing myogenic precursors, which produce progenitor cells of the embryonic and foetal body muscles (Gros et al., 2005; Kassar-Duchossoy et al., 2005; Relaix et al., 2005).”
Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis (2011, background): “As compound PAX3 and PAX7 mutants show a severe disruption of muscle development at later stages, with very few differentiated muscle cell”
Building muscle: molecular regulation of myogenesis. (2012, methodology): “It is now generally accepted that satellite cells are closely related to progenitors of somitic origin (Gros et al. 2005; Relaix et al. 2005; Schienda et al. 2006; Hutcheson et al. 2009; Lepper and Fan 2010).”
Satellite cells and the muscle stem cell niche. (2013, background): “These cells, which were absent from the primary myotome at earlier stages, count for the majority of all proliferating cells in embryonic/fetal trunk muscles (203, 434).”
Pax7 and myogenic progression in skeletal muscle satellite cells (2006, background): “This construct was used to make a transgenic mouse line in which the presence of -gal reports transcriptional activity of Pax3 and Pax7 (Relaix et al., 2003; Relaix et al., 2004).”
Enhancement of meat production by environmental manipulations in embryo and young broilers (2006, background): “However, a recent study has indicated that both Pax3 and Pax7 proteins are expressed in a group of muscle progenitor cells that adopt the satellite cell position in later stages of development (Relaix et al., 2005).”
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells (2006, methodology): “It is only when both Pax3 and -7 are absent that these cells die or fail to enter the myogenic program, with a major deficit in skeletal muscle in the double mutant (Relaix et al., 2005).”
Satellite Cells and Skeletal Muscle Regeneration (2015, positive): “While most Pax3/7 + cells express MRFs and commit to myogenic progenitors during development, there is a subset of Pax3/7 + cells that proliferates without upregulating the different MRFs (152,246).”
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7 (2010, background): “Gene targeting studies show that satellite cells that lack Pax7 and its close homologue, Pax3, die or differentiate into cartilage and other cell types (Relaix et al., 2005).”