The Arabidopsis TT2 Gene Encodes an R2R3 MYB Domain Protein That Acts as a Key Determinant for Proanthocyanidin Accumulation in Developing Seed

By N. Nesi, Clarisse Jond, I. Debeaujon, Michel Caboche, Loïc Lepiniec. The Plant Cell Online, 2001

805 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/bbddbab80e00734fd865675d6ed22dac88b243e8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Plant Science

Citations in the corpus

Sucrose-Specific Induction of the Anthocyanin Biosynthetic Pathway in Arabidopsis[W] (2005, background): “The DFR expression is also under the control of TT2, interacting with TT8 (Nesi et al., 2001).”
Light-Induced Expression of a MYB Gene Regulates Anthocyanin Biosynthesis in Red Apples1 (2006, background): “For example, AtPAP1 and AtPAP2, which regulate anthocyanin synthesis, and AtTT2, which regulates CT synthesis, are specific for regulation of these branches of the flavonoid pathway (Borevitz et al., 2000; Nesi et al., 2001).”
Biosynthesis and Regulation of Phenylpropanoids in Plants (2017, background): “They supply pigmentations to flowers, fruits and seeds to attract pollinators and seed dispersers (Nesi et al., 2001; Williams et al., 2004; Buer et al., 2010; Saito et al., 2013; Shi and Xie, 2014).”
Seed Coat Development and Dormancy (2007, background): “…BAN (ANR), TT3 (DFR) and TT18 (LDOX) genes was absent in mutants defective in TT2 (MYB), TT8 (bHLH) and TTG1 (WD40), suggesting regulatory roles for these transcription factors in the induction of PA biosynthesis and transport enzymes (Nesi et al., 2000; Nesi et al., 2001; Debeaujon et al., 2003).”
Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling (2007, background): “The seed-specific R2R3-MYB factor TRANSPARENT TESTA2 (TT2/MYB123) (Nesi et al., 2001) also needs the interaction with a BHLH factor, namely TT8/BHLH42 (Nesi et al., 2000), to activate the target genes DFR, BANYULS (BAN) and the multidrug and toxic compound extrusion (MATE)-type transporter TT12.”
The identification of flavonoids and the expression of genes of anthocyanin biosynthesis in the chrysanthemum flowers (2012, background): “1), genes encoding these enzymes have been isolated from many plants (Nesi et al. 2001).”
Seed coats: Structure, development, composition, and biotechnology (2005, background): “In the control of seed coat pigmentation, TTG1 interacts with the bHLH protein TT8 and the R2R3 MYB protein TT2 (Zhang et al., 2003).”
Evolutionary and comparative analysis of MYB and bHLH plant transcription factors. (2011, background): “Other branches of the phenylpropanoid pathway include proanthocyanidin (PA) biosynthesis, which is controlled by TT2 in the Arabidopsis seed coat (Nesi et al., 2001).”
Recent advances in the transcriptional regulation of the flavonoid biosynthetic pathway. (2011, background): “Regulators of PA biosynthesis have been identified in Arabidopsis (Nesi et al., 2001), grapevine (Bogs et al.”
The MYB Transcription Factor Superfamily of Arabidopsis: Expression Analysis and Phylogenetic Comparison with the Rice MYB Family (2005, background): “…et al., 1994; Bender and Fink, 1998; Hoeren et al., 1998; Mol et al., 1998, Tamagnone et al., 1998; Borevitz et al., 2000; Jin et al., 2000; Nesi et al., 2001; Baudry et al., 2004), the control of cell morphogenesis (Oppenheimer et al., 1991, Noda et al., 1994; Glover et al., 1998; Payne…”
Red grain colour gene (R) of wheat is a Myb-type transcription factor (2005, background): “Tamyb10 showed similarity to tt2 (myb-type factor) of Arabidopsis, which controls the expression of the late genes in the flavonoid pathway (Nesi et al., 2001).”