Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens.

By S. Nicola, D. Surmeier, R. Malenka. Annual Review of Neuroscience, 2000

996 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/bbb2b34743f8a79c0c154932243a65f44a07d31c

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In Cellular and Molecular Neuroscience

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Citations in the corpus

Pathological synchronization in Parkinson's disease: networks, models and treatments. (2007, background): “The increased firing of MSNs might result from the absence of modulation by dopamine of their intrinsic K+ currents, afferent glutamatergic EPSPs and local GABAergic IPSPs [ 14 ].”
Dynamic Dopamine Modulation in the Basal Ganglia: A Neurocomputational Account of Cognitive Deficits in Medicated and Nonmedicated Parkinsonism (2005, background): “This functionality also helps to string simple motor commands together to form a complex motor sequence, by selecting the most appropriate command at any given portion of the sequence and inhibiting the other ones until the time is appropriate.”
Cortico–basal ganglia circuit mechanism for a decision threshold in reaction time tasks (2006, background): “In addition, the striatum is the recipient of prominent projections from midbrain dopamine neuron”
Addiction and the brain: The neurobiology of compulsion and its persistence (2001, background): “, perhaps because dopamine mediates the depression of glutamate release, even during an LTP-inducing tetanu”
Striatal plasticity and basal ganglia circuit function (2008, background): “Despite the critical role of dopamine in striatal function, surprisingly there is no firm evidence for direct presynaptic modulation of glutamate release by dopamine in the dorsal striatum (Nicola et al., 2000).”
Motivation and cognitive control: from behavior to neural mechanism. (2015, background): “In particular, DA is known to have a range of effects on cellular physiology, such as altering neuronal excitability (Henze et al. 2000, Nicola et al. 2000) and enhancing the signal-to-noise ratio (Durstewitz & Seamans 2008, Thurley et al. 2008).”
Brain circuitry and the reinstatement of cocaine-seeking behavior (2003, background): “Exactly how these two adaptations may mediate drug-seeking behavior is difficult to discern as the electrophysiological actions of dopamine in the accumbens vary depending on the level of convergent excitatory input (Nicola et al. 2000; Goto and O’Donnell 2001).”
Dopaminergic modulation of synaptic transmission in cortex and striatum (2012, background): “These studies invariably reported complex, variable, and often contradictory findings (see Nicola et al., 2000; Seamans and Yang, 2004 for review).”
Frontiers in Synaptic Neuroscience Synaptic Neuroscience (positive): “As a result, many different voltagegated and calcium-dependent ion channels are influenced, which can affect membrane potential, neuronal spiking and excitatory transmission as well as inhibitory transmission (for review, see: Hasselmo, 1995; Nicola et al., 2000; Magee and Johnston, 2005; Sara, 2009”
Cortico-Basal Ganglia Reward Network: Microcircuitry (2009, positive): “…parts of the basal forebrain and hypothalamus may serve the role of output structures for visceral motor functions, with projections to them arising directly from the NAc (and producing inhibition) or indirectly through the VP (and ultimately producing disinhibition) (Nicola et al, 2000).”
Dopamine and the regulation of cognition and attention. (2002, background): “Moreover, D1 receptor activation affects calcium currents (Nicola et al., 2000).”
Neuromodulated Spike-Timing-Dependent Plasticity, and Theory of Three-Factor Learning Rules (2016, background): “The multiple ways in which neuromodulators can interact with neural activity (Kaczmarek and Levitan, 1987; Nicola et al., 2000; Marder, 2012; Nadim and Bucher, 2014) combined with complex network structures suggest many different mechanisms of interplay between them (Marder, 2012).”
Making Working Memory Work: A Computational Model of Learning in the Prefrontal Cortex and Basal Ganglia (2006, background): “To reflect the finding that DA modulation has a contrastenhancing function in the striatum (Frank, 2005; Nicola, Surmeier, & Malenka, 2000; Hernandez-Lopez, Bargas, Surmeier, Reyes, & Galarraga, 1997), and to produce more of a credit-assignment effect in learning, the DA modulation is partially a ”