The chromatin remodelling factor Brg‐1 interacts with β‐catenin to promote target gene activation

By Nick Barker, A. Hurlstone, Hannah Musisi, A. Miles, M. Bienz, Hans Clevers. EMBO Journal, 2001

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Phospho-regulation of β-Catenin Adhesion and Signaling Functions (2007, background): “The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation.”
The Wnt signaling pathway in development and disease. (2004, background): “Another activator, Brg-1, is a component of the SWI/SNF (switching-defective and sucrose nonfermenting) chromatin remodeling complex which, with CBP, may induce chromatin remodeling that favors target gene transcription (Barker et al. 2001).”
Maternal β-catenin and E-cadherin in mouse development (2004, background): “βcatenin can also recruit the chromatin-remodeling factor BRG1 to TCF-responsive promoters, forming a complex to remodel chromatin and facilitate transcriptional activation (Barker et al., 2001; Nielsen et al., 2002).”
Wnt signaling: is the party in the nucleus? (2006, background): “Both -actin and actin-related proteins are integral subunits of chromatin remodeling complexes, including TRRAP/p400/TIP60 and TRRAP/ GCN5 (SAGA), INO80, and SWI/SNF-like BAF/Brg-1containing complexes, several of which are already known to be required for Wnt transcription.”
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer (2009, unknown): “relaxation to efficiently initiate transcription [58–61].”