Ultrafast optogenetic control

By Lisa A. Gunaydin, Ofer Yizhar, Andre Berndt, V. Sohal, Karl Deisseroth, P. Hegemann. Nature Neuroscience, 2010

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The Development and Application of Optogenetics (2011, background): “In vitro, optogenetic tools are typically activated with filtered light from mercury arc lamps (e.g., Berndt et al. 2009, Boyden et al. 2005, Gunaydin et al. 2010), lasers (Cardin et al. 2010, Cruikshank et al. 2010, Kravitz et al. 2010, Petreanu et al. 2009), light-emitting diodes (LEDs) (e.g.,…”
Closed-loop and activity-guided optogenetic control. (2015, positive): “It is also important to note that the choice of actuator will constrain the range of firing rates that can be evoked (and the latency and jitter), defining the range of patterns that can be reliably controlled (Mattis et al., 2012; Gunaydin et al., 2010).”
Molecular and cellular approaches for diversifying and extending optogenetics. (2010, background): “Other possibilities such as shifted action spectrum (Zhang et al., 2008; Gunaydin et al., 2010), increased two-photon responsivity, and altered ion permeability (e.g., for Ca2+) may also be achieved in the future.”
Whole-brain mapping of direct inputs to midbrain dopamine neurons. (2012, positive): “Next, to examine the specificity of the initial infection and to verify that the transsynaptic spread is under the tight control of RG expression, we repeated the experiment without AAV8-FLEX-RG in DAT-Cre mice.”