BIC and miR‐155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas

By J. Kluiver, S. Poppema, D. de Jong, T. Blokzijl, G. Harms, Susan Jacobs, B. Kroesen, A. van den Berg. Journal of Pathology, 2005

735 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/b85579b99dbbb684698306c6a3aa62f312ed88ba

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

In Molecular Biology

In Pathology and Forensic Medicine

Citations in the corpus

The biology of Hodgkin's lymphoma (2009, background): “Finally, we are also beginning to understand that deregulated expression of microRNAs may contribut”
microRNAs in cancer (2013, background): “In humans, BIC RNA levels are low in normal lymphoid tissues but increase in various B cell malignancies, including Hodgkin lymphoma and some subtypes of non-Hodgkin lymphoma (70, 125).”
MicroRNA signatures in human cancers (2006, background): “This gene is overexpressed in various types of B-cell malignanc”
Oncomirs — microRNAs with a role in cancer (2006, background): “gov/cancertopics/types/hodgkinslymphoma">Hodgkin lymphoma and in primary mediastinal and diffuse large-B-cell lymphomas with activated rather than germinal-centre phenotype”
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. (2007, background): “MiR-155 is also overexpressed in solid tumors such as those of the colon, lung, and breast,(4,7) while being associated with the activated B-cell type of diffuse large B-cell lymphoma as well as Hodgkin and Burkitt lymphoma.(15,16) It has also been shown to be involved in leukemogenesis in transgeni”
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. (2008, background): “Studies have shown that miR-155 accumulates in chronic lymphocytic leukemia (34), lymphomas (30, 35 ), breast cancer, and pancreatic cancer (36,37).”
Detection of elevated levels of tumour‐associated microRNAs in serum of patients with diffuse large B‐cell lymphoma (2008, background): “For example MIRN155, in addition to being upregulated in certain lymphomas but not others (Kluiver et al, 2005), is necessary for normal immune function (Rodriguez et al, 2007).”
miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis (2020, background): “For example, miR-155 was first considered an oncomiR for lymphoma and pancreatic cancer [113,114], but other evidence suggests that in the cases of ovarian and gastric cancers and melanoma, its expression is inhibited, therefore acting like a tumor suppressor [115–117].”
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype (2007, background): “Notably, one miRNA, miR155, is differentially expressed in ER- versus ER+ tumors (Figure 3), overexpressed in breast tumors compared to normal controls [77,78] and additionally other tumor types, suggesting that this miRNA may have diagnostic potential beyond breast cancer [54,91-93].”