A unified hypothesis on the lineage of neural stem cells

By Arturo Alvarez-Buylla, Jose Manuel García-Verdugo, A. D. Tramontin. Nature Reviews Neuroscience, 2001

1,056 citations recorded by the source corpus.

Subfields: Cancer Research, Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/b73c723c616784a125a90f4117a2589ba0ef4f95

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Citations in the corpus

Astrocytes Give Rise to New Neurons in the Adult Mammalian Hippocampus (2001, background): “Therefore, neural stem cells are probably contained within the lineage: “neuroepithelium-radial glia-astrocytes” ( Alvarez-Buylla et al., 2001 ).”
Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “An emerging hypothesis is that stem cells are contained within the astrocyte lineage (Alvarez-Buylla et al. 2001; Doetsch 2003a).”
hGFAP‐cre transgenic mice for manipulation of glial and neuronal function in vivo (2001, background): “…that GFAP-positive cells are indeed multipotential (Johansson et al., 1999; Doetsch et al., 1999; Laywell et al., 2000), and radial glia may be a normal developmental path toward both neurons and astrocytes (Malatesta et al., 2000; Noctor et al., 2001) (reviewed in Alvarez-Buylla et al., 2001).”
Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains (2010, background): “In the adult brain, neural stem cells exist in two regions, the subventricular zone (SVZ) of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus, and neurogenesis occurs continuously in these two regions (Alvarez-Buylla et al., 2001; Doetsch, 2003).”
Systematic analysis of neural projections reveals clonal composition of the Drosophila brain. (2013, neutral): “Neuronal and glial lineages are mixed in the mammalian brain [53], and at least some Drosophila lineages produce both neurons and glia [21, 54].”
Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embryogenesis (2005, result): “This finding further supports the central role that radial glial cells play as progenitors during development (Alvarez-Buylla et al., 2001).”
Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell (2005, background): “However, recent fate mapping analysis [69] indicates that a subset of radial glia give rise to the sub-ventricular zone astrocytes that function as adult neural stem cells [70,71].”
Is adult neurogenesis essential for olfaction? (2011, neutral): “and Alvarez-Buylla, A. (2009) The glial nature of embryonic and adult neural stem cells.”