Chromatin remodelling: the industrial revolution of DNA around histones

By Anjanabha Saha, J. Wittmeyer, B. Cairns. Nature reviews. Molecular cell biology, 2006

645 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/b680a76a119ef4770abdc987202345006f333878

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Citations in the corpus

The Major Architects of Chromatin: Architectural Proteins in Bacteria, Archaea and Eukaryotes (2008, background): “These large (several MDa) complexes convert chemical energy from ATP hydrolysis into mechanical motion by forcing DNA around the nucleosome and thereby disrupting histone-DNA contacts (Saha et al., 2006).”
ACF catalyses chromatosome movements in chromatin fibres (2008, background): “Similarly, one would expect ATPdependent nucleosome repositioning to be difficult in the presence of linker histones, as this is likely to involve pulling linker DNA into the nucleosome (Flaus and Owen-Hughes, 2004; Saha et al, 2006).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “In order to get access to the relevant segments of DNA for various processes in DNA metabolism, eukaryotic cells use ATP-dependent chromatin-remodeling enzymes (CRE) which alter the structure and/or position of the nucleosomes [182, 1960, 1961, 1962, 1963, 1964, 1965, 1966, 1967].”
The role of chromatin during transcription. (2007, background): “…major class of chromatin regulators are the protein complexes that utilize ATP hydrolysis to alter the histone-DNA contacts; because of this, they are generally referred to as chromatin-remodeling complexes (See reviews Flaus and Owen-Hughes, 2004; Saha et al., 2006; Smith and Peterson, 2005).”
SWI/SNF nucleosome remodellers and cancer (2011, background): “SWI/SNF complexes remodel nucleosome structure and are capable of mobilizing nucleosomes both by sliding and by catalysing the ejection and insertion of histone octamer”